about
The role of Cdc25A in the regulation of cell proliferation and apoptosisInvestigational inhibitors of PTP4A3 phosphatase as antineoplastic agents.A novel mechanism of indole-3-carbinol effects on breast carcinogenesis involves induction of Cdc25A degradationGeneFriends: an online co-expression analysis tool to identify novel gene targets for aging and complex diseases.Multicellular tumor spheroid models to explore cell cycle checkpoints in 3D.Targeting protein tyrosine phosphatases for anticancer drug discovery.Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease.Targeting CDC25C, PLK1 and CHEK1 to overcome Docetaxel resistance induced by loss of LZTS1 in prostate cancer.G2/M accumulation in prostate cancer cell line PC-3 is induced by Cdc25 inhibitor 7-chloro-6-(2-morpholin-4-ylethylamino) quinoline-5, 8-dione (DA 3003-2).CDC25A mRNA levels significantly correlate with Ki-67 expression in human glioma samples.Flexibility and inhibitor binding in cdc25 phosphatases.Conformational flexibility of the complete catalytic domain of Cdc25B phosphatases.New Approaches to Difficult Drug Targets: The Phosphatase Story
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Is Cdc25 a druggable target?
@en
Is Cdc25 a druggable target?
@nl
type
label
Is Cdc25 a druggable target?
@en
Is Cdc25 a druggable target?
@nl
prefLabel
Is Cdc25 a druggable target?
@en
Is Cdc25 a druggable target?
@nl
P2860
P1476
Is Cdc25 a druggable target?
@en
P2860
P304
P356
10.2174/187152008786847738
P577
2008-12-01T00:00:00Z