TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
about
miR-22 forms a regulatory loop in PTEN/AKT pathway and modulates signaling kineticsThe endothelium abridges insulin resistance to premature agingThe role of epigenetics in the pathology of diabetic complicationsMicroRNA dysregulation in diabetic ischemic heart failure patientsA coding-independent function of gene and pseudogene mRNAs regulates tumour biologyRedox Regulation in Cancer Stem CellsRole of regulatory micro RNAs in type 2 diabetes mellitus-related inflammationMicroRNAs: new insights into chronic childhood diseasesRecent developments in myofibroblast biology: paradigms for connective tissue remodelingActin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving functionHuman genetics of diabetic vascular complicationsMicroRNAs in Diabetic Kidney DiseaseEpigenetics of progression of chronic kidney disease: fact or fantasy?Emerging role of microRNAs in liver diseasesTherapeutic targeting of cancers with loss of PTEN function.High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cellsMini-review: emerging roles of microRNAs in the pathophysiology of renal diseasesmicroRNAs in kidneys: biogenesis, regulation, and pathophysiological rolesModeling of miRNA and drug action in the EGFR signaling pathwayEpigenetic histone methylation modulates fibrotic gene expressionMicroRNA-23a promotes myelination in the central nervous systemNetSlim: high-confidence curated signaling mapsTGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansionEMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancerMechanisms of fibrosis: therapeutic translation for fibrotic diseaseMicroRNA-23b Targets Ras GTPase-Activating Protein SH3 Domain-Binding Protein 2 to Alleviate Fibrosis and Albuminuria in Diabetic NephropathyMiR-217 mediates the protective effects of the dopamine D2 receptor on fibrosis in human renal proximal tubule cells.microRNA in the development of diabetic complications.Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesismiR-217 regulates ethanol-induced hepatic inflammation by disrupting sirtuin 1-lipin-1 signaling.MicroRNA-217 promotes ethanol-induced fat accumulation in hepatocytes by down-regulating SIRT1.MiRNAs in kidney transplantation: potential role as new biomarkers.MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cellsTGFβR2 is a major target of miR-93 in nasopharyngeal carcinoma aggressiveness.MicroRNA-192 suppresses liver metastasis of colon cancer.miR-217 inhibits triple-negative breast cancer cell growth, migration, and invasion through targeting KLF5Expression of ovine herpesvirus -2 encoded microRNAs in an immortalised bovine - cell line.TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucomaTGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEIRegulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486
P2860
Q21091130-B52A7E6C-D7AC-4E4F-A2CA-8F8A4876405FQ24605364-9A9F7075-44EC-4EA9-9956-00067C241A1EQ24609124-DDF2AEAB-3844-492A-AA71-52CC43897FE8Q24618462-9B90EB5B-2131-471B-A07E-4E9509CFA50DQ24632651-CDABC9D2-6BC2-4B07-98BE-2B97C38F71E0Q26798198-B839DD3B-046F-4211-A9B6-E55AD6259FCDQ26830676-8B747082-C68F-4CB9-AE38-D86BB721402DQ26852909-D9F8D474-A765-4A1B-BCA2-78F261B07D50Q26863751-0514C963-7BF9-4558-AFFB-71483069FF17Q26866068-1BA8A4B7-9890-4108-AA69-4788898CA618Q27000709-BA67F9C5-49B2-4A4E-B9DB-0150A141F3DAQ27002171-932A5C50-F622-440A-B8C6-B1A4B69A7463Q27005788-903307DB-6487-41FE-9905-69D6010F6B6EQ27490492-C7E0F082-3412-4187-81C6-A4509DE5B5FBQ27852764-699A98F8-A7F5-47BA-9179-7807AEFA08D5Q28119012-A724F56E-6549-4958-9F7D-9A9E1699D145Q28354033-47A99BAD-C34D-4798-A860-E50798AADF57Q28387168-F764CF37-7DC7-4295-8E22-359E22634E89Q28478852-E574CC5F-6CBC-4922-8E99-7EC8BB6DF3B4Q28579049-1E1EC655-0225-43D8-A7A3-7E71261D5C67Q28589529-01A9028D-DD79-425B-BD95-BE136069CE51Q28732508-52F8A302-CBC0-4EC0-A7D8-30CEAEFC8B5BQ28975741-84AE930D-2B50-4B9F-9101-A7E4F606E00EQ29616360-065FCFE0-043B-41B5-ABEA-90CA4EB8E3D1Q29620307-566A387D-D0A1-4C38-A865-A9B361114E46Q30009025-DDF77944-D945-416B-BA21-05D9F1AEC594Q30300319-85B6BBE2-93CB-49DE-ADD1-8B083FDC8D30Q30353835-2B207729-CF9C-45C9-810D-54E6F8B19101Q30354729-DAB500DF-0EAB-4ED9-801A-4D5CCA6BFABBQ30359251-2DC9B418-4C47-4F52-9B86-42AB79893CD0Q30421790-3C5A4B1B-819E-4F8C-8528-BC68BD2FB7DBQ30456341-5EE9C1F5-10CA-4B31-8420-972EE67FF125Q31047754-325E6FB8-D565-43D9-BB22-97A662BD9930Q33592822-1DFFB315-1F59-476C-96DC-47EA24C4246AQ33594662-5F8153D2-B881-4E0B-B9D9-E23FEAE20C9BQ33596743-A4C3D344-D37C-41D2-8A53-E92375D660B3Q33645514-1176992C-A8F0-4297-82FE-7E747886FCAEQ33678064-313CBA33-DCC0-4195-A2DC-5180016CFF5FQ33696388-3BCEBEA2-6A42-452A-9280-75BD0AE03861Q33732748-3A629E63-56DC-4005-A176-B887007CAD96
P2860
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 June 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TGF-beta activates Akt kinase ...... lifying circuit targeting PTEN
@en
TGF-beta activates Akt kinase ...... ifying circuit targeting PTEN.
@nl
type
label
TGF-beta activates Akt kinase ...... lifying circuit targeting PTEN
@en
TGF-beta activates Akt kinase ...... ifying circuit targeting PTEN.
@nl
prefLabel
TGF-beta activates Akt kinase ...... lifying circuit targeting PTEN
@en
TGF-beta activates Akt kinase ...... ifying circuit targeting PTEN.
@nl
P2093
P2860
P356
P1433
P1476
TGF-beta activates Akt kinase ...... lifying circuit targeting PTEN
@en
P2093
Amanda Gunn
Hitoshi Shimano
Ivan Todorov
John J Rossi
Linda Lanting
Rama Natarajan
Sumanth Putta
P2860
P2888
P304
P356
10.1038/NCB1897
P50
P577
2009-06-21T00:00:00Z