Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response.
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialL-type calcium channels as drug targets in CNS disordersRegulation of Cardiac Calcium Channels in the Fight-or-Flight ResponseBasal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial FibrillationCardiac T-Tubule Microanatomy and Function.Cell-type-specific tuning of Cav1.3 Ca(2+)-channels by a C-terminal automodulatory domain.Phosphorylation sites in the Hook domain of CaVβ subunits differentially modulate CaV1.2 channel functionFinding Channels.Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads.Calcium Sparks in the Heart: Dynamics and Regulation.K(ATP) channel gain-of-function leads to increased myocardial L-type Ca(2+) current and contractility in Cantu syndrome.Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacologyLoss of β-adrenergic-stimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failureDifferential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150.Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the β2-adrenergic receptor in neurons.L-type Ca2+ channels in heart and brainProteolytic cleavage and PKA phosphorylation of α1C subunit are not required for adrenergic regulation of CaV1.2 in the heart.A new phosphorylation site in cardiac L-type Ca2+ channels (Cav1.2) responsible for its cAMP-mediated modulation.Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.Calmodulin and ATP support activity of the Cav1.2 channel through dynamic interactions with the channel.The rice CK2 kinase regulates trafficking of phosphate transporters in response to phosphate levels.Identification of a novel cAMP dependent protein kinase A phosphorylation site on the human cardiac calcium channel.Protein kinase A regulates C-terminally truncated CaV 1.2 in Xenopus oocytes: roles of N- and C-termini of the α1C subunit.The AKAP Cypher/Zasp contributes to β-adrenergic/PKA stimulation of cardiac CaV1.2 calcium channels.Voltage-gated calcium channels: their discovery, function and importance as drug targets
P2860
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P2860
Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response.
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Phosphorylation sites required ...... the fight-or-flight response.
@en
Phosphorylation sites required ...... the fight-or-flight response.
@nl
type
label
Phosphorylation sites required ...... the fight-or-flight response.
@en
Phosphorylation sites required ...... the fight-or-flight response.
@nl
prefLabel
Phosphorylation sites required ...... the fight-or-flight response.
@en
Phosphorylation sites required ...... the fight-or-flight response.
@nl
P2093
P2860
P356
P1476
Phosphorylation sites required ...... the fight-or-flight response.
@en
P2093
Ruth E Westenbroek
Todd Scheuer
William A Catterall
P2860
P304
19621-19626
P356
10.1073/PNAS.1319421110
P407
P577
2013-11-11T00:00:00Z