Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.
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A direct interaction between Cdc42 and vesicle-associated membrane protein 2 regulates SNARE-dependent insulin exocytosisThe 'invisible hand': regulation of RHO GTPases by RHOGDIsExpression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cellsHigh glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunitCool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretionT-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretionGlucose controls morphodynamics of LPS-stimulated macrophages.Glucose activates prenyltransferases in pancreatic islet beta-cells.Differential phosphorylation of RhoGDI mediates the distinct cycling of Cdc42 and Rac1 to regulate second-phase insulin secretion.YES, a Src family kinase, is a proximal glucose-specific activator of cell division cycle control protein 42 (Cdc42) in pancreatic islet β cellsProtein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.Small G proteins in islet beta-cell function.A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110αPhagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation.Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective.Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets.A farnesylated G-protein suppresses Akt phosphorylation in INS 832/13 cells and normal rat islets: regulation by pertussis toxin and PGE₂.Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells.Protein histidine [de]phosphorylation in insulin secretion: abnormalities in models of impaired insulin secretion.Regulatory roles for small G proteins in the pancreatic beta-cell: lessons from models of impaired insulin secretion.EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells.Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.Techniques for studying protein heterogeneity and post-translational modifications.Cytoophidium assembly reflects upregulation of IMPDH activity.Role of lipooligosaccharide in Opa-independent invasion of Neisseria gonorrhoeae into human epithelial cells.Bridging the gap between protein carboxyl methylation and phospholipid methylation to understand glucose-stimulated insulin secretion from the pancreatic beta cell.Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretionNm23-H1 regulates glucose-stimulated insulin secretion in pancreatic β-cells via Arf6-Rac1 signaling axis.Glucose activates the carboxyl methylation of gamma subunits of trimeric GTP-binding proteins in pancreatic beta cells. Modulation in vivo by calcium, GTP, and pertussis toxin.Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins.Interplay between Rab27a effectors in pancreatic β-cells.Activated Cdc42-bound IQGAP1 determines the cellular endocytic siteExocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion.Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction.Biologically active lipids promote trafficking and membrane association of Rac1 in insulin-secreting INS 832/13 cells.Caveolin-1 functions as a novel Cdc42 guanine nucleotide dissociation inhibitor in pancreatic beta-cells.Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells.
P2860
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P2860
Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@en
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@nl
type
label
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@en
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@nl
prefLabel
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@en
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@nl
P2093
P2860
P921
P356
P1476
Glucose- and GTP-dependent sti ...... ent-induced insulin secretion.
@en
P2093
A J Weinhaus
J Vadakekalam
M E Rabaglia
R L Sorenson
S E Seavey
P2860
P304
P356
10.1172/JCI118822
P407
P577
1996-07-01T00:00:00Z