Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells.
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Regulation of endothelium-derived nitric oxide production by the protein kinase AktInsulin induces the release of vasodilator compounds from platelets by a nitric oxide-G kinase-VAMP-3-dependent pathwayInsulin impairs endothelium-dependent vasodilation independent of insulin sensitivity or lipid profileProtein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cellsApplication of 4,5-diaminofluorescein to reliably measure nitric oxide released from endothelial cellsin vitroEndothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor.Vascular disease in diabetic women: Why do they miss the female protection?Muscle perfusion: its measurement and role in metabolic regulationMetabolic actions of angiotensin II and insulin: a microvascular endothelial balancing actThe insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endotheliumBidirectional regulation of monocyte chemoattractant protein-1 gene at distinct sites of its promoter by nitric oxide in vascular smooth muscle cellsLong-term high-fat diet induces hippocampal microvascular insulin resistance and cognitive dysfunction.Insulin Enhances Endothelial Function Throughout the Arterial Tree in Healthy But Not Metabolic Syndrome Subjects.Muscle microvasculature's structural and functional specializations facilitate muscle metabolism.Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 diabetes?Adiponectin and insulin cross talk: the microvascular connection.The endothelial cell: an "early responder" in the development of insulin resistance.Insulin regulates its own delivery to skeletal muscle by feed-forward actions on the vasculature.Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension.Insulin and insulin-like growth factor-I receptors differentially mediate insulin-stimulated adhesion molecule production by endothelial cells.The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin actionImpaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle.Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinaseGrowth hormone exerts acute vascular effects independent of systemic or muscle insulin-like growth factor IInsulin at physiological concentrations increases microvascular perfusion in human myocardium.Insulin-mediated activation of the L-arginine nitric oxide pathway in man, and its impairment in diabetesPhosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to inGreen tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: roles for AMP-activated protein kinase, Akt, and FOXO1Central role of the adipocyte in insulin resistance.Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease.Enhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein-tyrosine phosphatases.The transcriptional response in human umbilical vein endothelial cells exposed to insulin: a dynamic gene expression approach.Sildenafil reduces insulin-resistance in human endothelial cellsSevere impairment of endothelial function with the HIV-1 protease inhibitor indinavir is not mediated by insulin resistance in healthy subjects.Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complicationsThe autoinhibitory control element and calmodulin conspire to provide physiological modulation of endothelial and neuronal nitric oxide synthase activity.Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.L-arginine as a nutritional prophylaxis against vascular endothelial dysfunction with aging.Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension.Obesity and autonomic function in adolescence.
P2860
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P2860
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Insulin-stimulated production ...... in vascular endothelial cells.
@en
Insulin-stimulated production ...... in vascular endothelial cells.
@nl
type
label
Insulin-stimulated production ...... in vascular endothelial cells.
@en
Insulin-stimulated production ...... in vascular endothelial cells.
@nl
prefLabel
Insulin-stimulated production ...... in vascular endothelial cells.
@en
Insulin-stimulated production ...... in vascular endothelial cells.
@nl
P2860
P356
P1476
Insulin-stimulated production ...... in vascular endothelial cells.
@en
P2860
P304
P356
10.1172/JCI118871
P407
P577
1996-08-01T00:00:00Z