Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes. - Wikidata - wikimedia - TriplyDB

Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes.

Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes.

http://www.wikidata.org/entity/Q37360404

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Mechanisms of Beta Cell Dysfunction Associated With Viral Infection Virus infections in type 1 diabetes Distinct cell clusters touching islet cells induce islet cell replication in association with over-expression of Regenerating Gene (REG) protein in fulminant type 1 diabetes Class II HLA genotype in fulminant type 1 diabetes: A nationwide survey with reference to glutamic acid decarboxylase antibodies.α1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1β responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.An Unusual Case of Fulminant Type 1 Diabetes during the Second Trimester of Pregnancy Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans.Fulminant type 1 diabetes in China: a case report and review of the literature.RIG-I- and MDA5-initiated innate immunity linked with adaptive immunity accelerates beta-cell death in fulminant type 1 diabetes Factors associated with the presence of diabetic ketoacidosis at diagnosis of diabetes in children and young adults: a systematic review.CXC chemokine ligand 10 DNA vaccination plus Complete Freund's Adjuvant reverses hyperglycemia in non-obese diabetic mice.Viral infection of engrafted human islets leads to diabetes.Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser-capture microdissection followed by mass spectrometry.Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes.Expression and regulation of chemokines in murine and human type 1 diabetes.Examination of a Viral Infection Mimetic Model in Human iPS Cell-Derived Insulin-Producing Cells and the Anti-Apoptotic Effect of GLP-1 Analogue Etiopathogenesis of insulin autoimmunity.TYK2 Promoter Variant and Diabetes Mellitus in the Japanese.Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes.Cytokine and chemokine production by human pancreatic islets upon enterovirus infection Dysregulated Toll-like receptor-induced interleukin-1β and interleukin-6 responses in subjects at risk for the development of type 1 diabetes USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis Immunological Aspects of Fulminant Type 1 Diabetes in Chinese.Immune regulation and evasion of Mammalian host cell immunity during viral infection.Functional redundancy of CXCR3/CXCL10 signaling in the recruitment of diabetogenic cytotoxic T lymphocytes to pancreatic islets in a virally induced autoimmune diabetes model Enterovirus infection of human islets of Langerhans affects β-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues.Enteroviruses in the pathogenesis of type 1 diabetes.Immunopathology of the human pancreas in type-I diabetes.Type 1 diabetes: etiology, immunology, and therapeutic strategies.Immunological perspective of self versus tumor antigens: insights from the RIP-gp model.Enteroviruses and causality of type 1 diabetes: how close are we?Fulminant type 1 diabetes--an important subtype in East Asia.Immunology in the clinic review series: focus on type 1 diabetes and viruses: the role of viruses in type 1 diabetes: a difficult dilemma.Viral infections and molecular mimicry in type 1 diabetes.Pancreatic pathology in type 1 diabetes mellitus.Death waits for no man--does it wait for a virus? How enteroviruses induce and control cell death High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3(+) T Memory Cells Reflecting an Enhanced Activity of Th1 Autoimmune Response.The Role of the Intestinal Microbiome in Type 1 Diabetes Pathogenesis.Recent Findings on Fulminant Type 1 Diabetes.

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Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes.

http://www.wikidata.org/entity/Q37360404

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article científic

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scientific article published on 29 July 2009

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Enterovirus infection, CXC che ...... in fulminant type 1 diabetes.

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Akio Kawaguchi

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Akira Shimada

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Daiichiro Akiyama

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Fumihiko Furuya

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Hiroki Shimura

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Kaoru Aida

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Masahiro Kaneshige

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Masako Suzuki

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Masashi Takahashi

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Ryohei Katoh

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P2860

Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

The many roles of chemokines and chemokine receptors in inflammation

Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients.

Comparison of classic and molecular approaches for the identification of untypeable enteroviruses.

Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues.

The prevalence of enteroviral capsid protein vp1 immunostaining in pancreatic islets in human type 1 diabetes.

Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens.

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

IP-10 and type 1 diabetes: a question of time and location.

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus.

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2285-2291

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10.2337/DB09-0091

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10

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2009-07-29T00:00:00Z

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26703931

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19641142

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type-1 diabetes

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2750208

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