Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection
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Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sortingThe coxsackievirus and adenovirus receptor is a transmembrane component of the tight junctionCaveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSMAdenoviral transduction of enterocytes and M-cells using in vitro models based on Caco-2 cells: the coxsackievirus and adenovirus receptor (CAR) mediates both apical and basolateral transductionIsoform-specific regulation and localization of the coxsackie and adenovirus receptor in human airway epitheliaDirected evolution of adeno-associated virus to an infectious respiratory virusStructural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptorHuman bocavirus: Current knowledge and future challengesAdenovirus membrane penetration: Tickling the tail of a sleeping dragonRecombinant GABA(C) receptors expressed in rat hippocampal neurons after infection with an adenovirus containing the human rho1 subunitA system for the propagation of adenoviral vectors with genetically modified receptor specificities.A novel peptide, THALWHT, for the targeting of human airway epithelia.General strategy for broadening adenovirus tropism.Improved gene delivery to intestinal mucosa by adenoviral vectors bearing subgroup B and d fibers.A replication-incompetent adenovirus vector with the preterminal protein gene deleted efficiently transduces mouse earsCoxsackievirus and adenovirus receptor amino-terminal immunoglobulin V-related domain binds adenovirus type 2 and fiber knob from adenovirus type 12Role of alpha(v) integrins in adenovirus cell entry and gene delivery.Transient inhibition of CD28 and CD40 ligand interactions prolongs adenovirus-mediated transgene expression in the lung and facilitates expression after secondary vector administrationGene transfer using recombinant rabbit hemorrhagic disease virus capsids with genetically modified DNA encapsidation capacity by addition of packaging sequences from the L1 or L2 protein of human papillomavirus type 16.Canine adenovirus type 2 attachment and internalization: coxsackievirus-adenovirus receptor, alternative receptors, and an RGD-independent pathway.Incorporation of adeno-associated virus in a calcium phosphate coprecipitate improves gene transfer to airway epithelia in vitro and in vivo.Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vectorEctodomain of coxsackievirus and adenovirus receptor genetically fused to epidermal growth factor mediates adenovirus targeting to epidermal growth factor receptor-positive cells.A chimeric type 2 adenovirus vector with a type 17 fiber enhances gene transfer to human airway epitheliaCAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts.Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactionsAdenovirus receptors and their implications in gene deliveryTargeting the urokinase plasminogen activator receptor enhances gene transfer to human airway epithelia.Imaging chemically modified adenovirus for targeting tumors expressing integrin alphavbeta3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene.Biodistribution of radioiodinated adenovirus fiber protein knob domain after intravenous injection in mice.Bronchoalveolar fluid is not a major hindrance to virus-mediated gene therapy in cystic fibrosis.Modulation of adenovirus vector tropism via incorporation of polypeptide ligands into the fiber protein.Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathologyEndosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.Overexpression of the epithelial Na+ channel gamma subunit in collecting duct cells: interactions of Liddle's mutations and steroids on expression and function.Transduction of the mammary epithelium with adenovirus vectors in vivo.Current status of gene therapy for inherited lung diseasesImplications of the innate immune response to adenovirus and adenoviral vectors.Access to nectin favors herpes simplex virus infection at the apical surface of polarized human epithelial cells.Species-specific differences in mouse and human airway epithelial biology of recombinant adeno-associated virus transduction.
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P2860
Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Lack of high affinity fiber re ...... thelia to adenovirus infection
@en
Lack of high affinity fiber re ...... helia to adenovirus infection.
@nl
type
label
Lack of high affinity fiber re ...... thelia to adenovirus infection
@en
Lack of high affinity fiber re ...... helia to adenovirus infection.
@nl
prefLabel
Lack of high affinity fiber re ...... thelia to adenovirus infection
@en
Lack of high affinity fiber re ...... helia to adenovirus infection.
@nl
P2093
P2860
P356
P1476
Lack of high affinity fiber re ...... thelia to adenovirus infection
@en
P2093
P2860
P304
P356
10.1172/JCI119625
P407
P577
1997-09-01T00:00:00Z