Novel alterations in CDK1/cyclin B1 kinase complex formation occur during the acquisition of a polyploid DNA content.
about
Regulation of CDC6, geminin, and CDT1 in human cells that undergo polyploidizationEndoreplication: polyploidy with purposeMolecular control of megakaryopoiesis and thrombopoiesis.Focal adhesion kinase is involved in mechanosensing during fibroblast migration.The incredible journey: From megakaryocyte development to platelet formation.Megakaryocytes and beyond: the birth of platelets.CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cellsA repertoire of cell cycle regulators whose expression is coordinated with human cytotrophoblast differentiationDownregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells.A role for cyclin D3 in the endomitotic cell cycleMOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy.Reprogramming the cell cycle for endoreduplication in rodent trophoblast cells.Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulansChromosome variation in the embryos of domestic animals.Cip/Kip cyclin-dependent protein kinase inhibitors and the road to polyploidy.Heterologous expression of the transcriptional regulator escargot inhibits megakaryocytic endomitosis.Phenotypic fingerprinting of small molecule cell cycle kinase inhibitors for drug discovery.Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1.S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.The transcription factor B-Myb is essential for S-phase progression and genomic stability in diploid and polyploid megakaryocytes.C-myc overexpression and p53 loss cooperate to promote genomic instability.Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes.Thrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis.PTHrP signaling targets cyclin D1 and induces osteoblastic cell growth arrest.Small Molecule Supplements Improve Cultured Megakaryocyte Polyploidization by Modulating Multiple Cell Cycle Regulators.Polyploidy road to therapy-induced cellular senescence and escape.
P2860
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P2860
Novel alterations in CDK1/cyclin B1 kinase complex formation occur during the acquisition of a polyploid DNA content.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 1996
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@en
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@nl
type
label
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@en
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@nl
prefLabel
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@en
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@nl
P2093
P2860
P356
P1476
Novel alterations in CDK1/cycl ...... on of a polyploid DNA content.
@en
P2093
P2860
P304
P356
10.1091/MBC.7.2.209
P577
1996-02-01T00:00:00Z