Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus.
about
Defect in glucokinase translocation in Zucker diabetic fatty ratsGlucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.Hepatic glucose sensing is impaired, but can be normalized, in people with impaired fasting glucose.Postprandial and fasting hepatic glucose fluxes in long-standing type 1 diabetes.Defective glycogenesis contributes toward the inability to suppress hepatic glucose production in response to hyperglycemia and hyperinsulinemia in zucker diabetic fatty ratsThe role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise.Modeling changes in glucose and glycerol rates of appearance when true basal rates of appearance cannot be readily determinedAntidiabetic Activity of Polysaccharides from Tuberous Root of Liriope spicata var. prolifera in KKAy MiceDifferences in insulin sensitivity and secretory capacity based on OGTT in subjects with impaired glucose regulation.Inhibiting gluconeogenesis prevents fatty acid-induced increases in endogenous glucose productionCNS regulation of glucose homeostasis.The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia.Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes.The regulation of glucose metabolism: implications and considerations for the assessment of glucose homeostasis in rodents.Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasisTargeting hepatic glucokinase in type 2 diabetes: weighing the benefits and risks.Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice.O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability.Renal glucose handling in diabetes and sodium glucose cotransporter 2 inhibition.Liver glucose-6-phosphatase proteins in suckling and weaned grey seal pups: structural similarities to other mammals and relationship to nutrition, insulin signalling and metabolite levels.Glucose transporter-1 in the hypothalamic glial cells mediates glucose sensing to regulate glucose production in vivoAn assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor GPi688 in rat models of hyperglycaemia.Overexpression of the P46 (T1) translocase component of the glucose-6-phosphatase complex in hepatocytes impairs glycogen accumulation via hydrolysis of glucose 1-phosphate.Activation of liver G-6-Pase in response to insulin-induced hypoglycemia or epinephrine infusion in the rat.Hepatic insulin resistance in obese non-diabetic subjects and in type 2 diabetic patients.Glucose-induced suppression of endogenous glucose production: dynamic response to differing glucose profiles.Induction of control genes in intestinal gluconeogenesis is sequential during fasting and maximal in diabetes.Hepatic glucose autoregulation: responses to small, non-insulin-induced changes in arterial glucose.Type 2 diabetic patients have increased gluconeogenic efficiency to substrate availability, but intact autoregulation of endogenous glucose production.Effects of hyperglycemia on glucose metabolism before and after oral glucose ingestion in normal men.Parenteral amino acids v. dextrose infusion: an anabolic strategy to minimise the catabolic response to surgery while maintaining normoglycaemia in diabetes mellitus type 2 patients.Correcting Postprandial Hyperglycemia in Zucker Diabetic Fatty Rats With an SGLT2 Inhibitor Restores Glucose Effectiveness in the Liver and Reduces Insulin Resistance in Skeletal Muscle.Elevated NEFA levels impair glucose effectiveness by increasing net hepatic glycogenolysis.A defect in glucose-induced dissociation of glucokinase from the regulatory protein in Zucker diabetic fatty rats in the early stage of diabetes.Mechanisms by which insulin, associated or not with glucose, may inhibit hepatic glucose production in the rat.
P2860
Q28574747-C730E10E-75DC-44A4-A6B0-B9592A9374F3Q33701505-89E9BF0F-652C-477B-ADFA-FF1BC69B4CFCQ33837104-DA4DDD9E-5E9B-44CC-9313-1E1AC96B074AQ35043435-141A2B3B-039B-4F63-8B5D-AB050FD4E3EDQ35180025-D0AC7C81-9251-4E33-BCCE-91670712C954Q35642128-EEB91932-DD77-456C-83EF-E75D56838AEDQ36637876-4EA04D62-4DF1-450F-B167-280071E2487EQ36916161-C569A88D-6EE6-4737-A295-1B9B7B462EF8Q37205376-4CFA1042-90DF-4047-BA75-BDAF86DF4392Q37264148-3528349D-B48F-431D-91CB-652245D7E3FBQ37512891-8EFCD386-E0B7-466D-B1C8-45A5ED3BB22AQ37940036-175E9B16-9165-42F5-97BE-91AA2A437AF3Q38071706-A10C28A4-8B31-4397-9E80-F9B40475C2CBQ38247935-C89F3510-2E4B-49A5-865B-5512E4C7C164Q39221068-1F00140A-A40E-4CD5-BA3C-A0AA5F0D2638Q41866371-4D8FC644-BFD6-470B-8342-461D6245AAA8Q41905656-F2F90F74-2597-4C30-9224-D49C3A6D0E56Q42076002-FA6E9415-53C9-455C-89BB-3751B32ADA3BQ42554440-96827698-58E3-4E9F-9E06-B6C4FFA9A2F6Q42602503-80240DA0-AF1B-44A4-8E8F-7B3EE276169EQ42770564-7F29F066-1E3E-4BB9-9C3C-C973F1C32A3DQ42940455-4AC98F52-98C0-418E-BD8D-BC1DAB7A2F8EQ43517004-2FBF423F-2BC7-4843-82A0-45D288399B7EQ43908156-43AF1364-16D2-4581-9C18-AEAD5B8DF6F4Q43911352-C412774A-1896-4599-8964-0373FC73B524Q44361959-01E6F404-9B38-4DCB-ABD1-C2CBBBC812E6Q44618181-8F59A2B3-DB6A-4E6C-A50D-60BD3CB7D46DQ44822011-3B2D6340-8585-4EA5-B880-03AF5AD8E1EEQ46632067-F3BA8B2A-C90E-4E0E-867B-FE3D5C5E0ABDQ46877806-042F75D5-0121-4894-A186-92D6FC529B81Q48238199-6E957117-7AF7-49CE-8837-B7EF9CBA6A53Q51118064-6E227D3F-1F7E-466C-AB1F-F06CE000318BQ51353301-0E532412-0DA2-4A7C-A066-AF6F78F438DEQ51481798-F86CA1BE-8FD3-4DC4-83E5-4DC903FFBA46Q51559333-FCEB8585-ECD2-4E77-8B6E-669EAEB15594
P2860
Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@en
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@nl
type
label
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@en
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@nl
prefLabel
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@en
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@nl
P2093
P2860
P921
P356
P1476
Regulation of endogenous gluco ...... d in type 2 diabetes mellitus.
@en
P2093
P2860
P304
P356
10.1172/JCI2720
P407
P577
1998-08-01T00:00:00Z