A genomic screen identifies TYRO3 as a MITF regulator in melanoma. - Wikidata - wikimedia - TriplyDB

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

http://www.wikidata.org/entity/Q37386014

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Pathways and therapeutic targets in melanoma MERTK receptor tyrosine kinase is a therapeutic target in melanoma.Kaliziri extract upregulates tyrosinase, TRP-1, TRP-2 and MITF expression in murine B16 melanoma cells.Sox proteins in melanocyte development and melanoma.PRKX, TTBK2 and RSK4 expression causes Sunitinib resistance in kidney carcinoma- and melanoma-cell lines.Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells.Phosphoproteomic screen identifies potential therapeutic targets in melanoma.MITF in melanoma: mechanisms behind its expression and activity.Genome-wide transcriptome analysis of human epidermal melanocytes.Biology of the TAM receptors.The transcription factor RUNX2 regulates receptor tyrosine kinase expression in melanoma.MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL.TAM receptors Tyro3 and Mer as novel targets in colorectal cancer.Insights into the Role of PAX-3 in the Development of Melanocytes and Melanoma.Pathways of oncogene-induced senescence in human melanocytic cells Advances in melanoma senescence and potential clinical application.Receptor tyrosine kinases and their activation in melanoma.The three M's: melanoma, microphthalmia-associated transcription factor and microRNA.Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.Microphthalmia-associated transcription factor expression levels in melanoma cells contribute to cell invasion and proliferation.Autophagy-Dependent Crosstalk between GILT and PAX-3 Influences Radiation Sensitivity of Human Melanoma Cells.Tyro3 carboxyl terminal region confers stability and contains the autophosphorylation sites.Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration.TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy.Autocrine role for Gas6 with Tyro3 and Axl in leiomyosarcomas.Ribonucleotide reductase and thymidylate synthase or exogenous deoxyribonucleosides reduce DNA damage and senescence caused by C-MYC depletion.Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line.Protein signatures as potential surrogate biomarkers for stratification and prediction of treatment response in chronic myeloid leukemia patients.SOX10-MITF pathway activity in melanoma cells.Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcoma.Tyro3-mediated phosphorylation of ACTN4 at tyrosines is FAK-dependent and decreases susceptibility to cleavage by m-Calpain.Pathways from senescence to melanoma: focus on MITF sumoylation.Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer.MicroRNA-7 inhibits colorectal cancer cell proliferation, migration and invasion via TYRO3 and phosphoinositide 3-kinase/protein B kinase/mammalian target of rapamycin pathway suppression

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A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

http://www.wikidata.org/entity/Q37386014

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 23 September 2009

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

@en

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

@nl

type

label

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

@en

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

@nl

prefLabel

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

@en

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

@nl

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PNAS.0909292106

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Proceedings of the National Academy of Sciences of the United States of America

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A genomic screen identifies TYRO3 as a MITF regulator in melanoma

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Anna Galkin

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Anthony Orth

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Buu P Tu

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Fanxiang Sun

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Feng Yan

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Heiko Wurdak

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Jie Li

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John Walker

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Loren Miraglia

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Peter G Schultz

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P2860

Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine kinase

Reevaluation of the roles of protein S and Gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3

Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB.

Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival

Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3

A tissue-restricted cAMP transcriptional response: SOX10 modulates alpha-melanocyte-stimulating hormone-triggered expression of microphthalmia-associated transcription factor in melanocytes

Acidification prevents endothelial cell apoptosis by Axl activation

Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl

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17025-17030

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scholarly article

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10.1073/PNAS.0909292106

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40

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106

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Costas A Lyssiotis

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2009-09-23T00:00:00Z

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26871295

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19805117

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2761329

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