Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias. - Wikidata - wikimedia - TriplyDB

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

http://www.wikidata.org/entity/Q37386101

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Map making in the 21st century: charting breast cancer susceptibility pathways in rodent models.Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.CHEK2 (∗) 1100delC Mutation and Risk of Prostate Cancer.CHK2 kinase in the DNA damage response and beyond Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex.CHEK2*1100delC homozygosity in the Netherlands--prevalence and risk of breast and lung cancer Homozygous inactivation of CHEK2 is linked to a familial case of multiple primary lung cancer with accompanying cancers in other organs.Cell cycle proteins as promising targets in cancer therapy Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease.

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Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

http://www.wikidata.org/entity/Q37386101

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 21 September 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

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Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

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type

label

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

@en

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

@nl

prefLabel

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

@en

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

@nl

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PNAS.0909237106

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Proceedings of the National Academy of Sciences of the United States of America

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Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

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El Mustapha Bahassi

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Gregory P Boivin

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Harry van Steeg

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Moying Yin

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Peter J Stambrook

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Susan B Robbins

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Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

Frequency of CHEK2 mutations in a population based, case-control study of breast cancer in young women

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway

The CHEK2 gene and inherited breast cancer susceptibility

Induction of mammary gland development in estrogen receptor-alpha knockout mice

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17111-17116

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scholarly article

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10.1073/PNAS.0909237106

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