Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation

Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation

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http://www.wikidata.org/entity/Q37396471
New approaches to management of neonatal hypoglycemiaEndocrine regulation of fetal skeletal muscle growth: impact on future metabolic healthFetal adrenal demedullation lowers circulating norepinephrine and attenuates growth restriction but not reduction of endocrine cell mass in an ovine model of intrauterine growth restrictionPlacental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheepAdrenal Demedullation and Oxygen Supplementation Independently Increase Glucose-Stimulated Insulin Concentrations in Fetal Sheep With Intrauterine Growth RestrictionIntrauterine growth-restricted sheep fetuses exhibit smaller hindlimb muscle fibers and lower proportions of insulin-sensitive Type I fibers near term.Chronic anemic hypoxemia increases plasma glucagon and hepatic PCK1 mRNA in late-gestation fetal sheep.Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep.Impact of placental insufficiency on fetal skeletal muscle growth.Challenges in nourishing the intrauterine growth-restricted foetus - Lessons learned from studies in the intrauterine growth-restricted foetal sheep.RNA Sequencing Exposes Adaptive and Immune Responses to Intrauterine Growth Restriction in Fetal Sheep Islets.Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine.Fetal adaptations in insulin secretion result from high catecholamines during placental insufficiency.Myoblasts from intrauterine growth-restricted sheep fetuses exhibit intrinsic deficiencies in proliferation that contribute to smaller semitendinosus myofibres.Chronic anemic hypoxemia attenuates glucose-stimulated insulin secretion in fetal sheep.The impact of IUGR on pancreatic islet development and β-cell function.Enhanced insulin secretion and insulin sensitivity in young lambs with placental insufficiency-induced intrauterine growth restriction.
P2860

Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation

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http://www.wikidata.org/entity/Q37396471
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Elevated plasma norepinephrine ...... ufficiency at 0.7 of gestation
@en
Elevated plasma norepinephrine ...... fficiency at 0.7 of gestation.
@nl
type
label
Elevated plasma norepinephrine ...... ufficiency at 0.7 of gestation
@en
Elevated plasma norepinephrine ...... fficiency at 0.7 of gestation.
@nl
prefLabel
Elevated plasma norepinephrine ...... ufficiency at 0.7 of gestation
@en
Elevated plasma norepinephrine ...... fficiency at 0.7 of gestation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
Elevated plasma norepinephrine ...... ufficiency at 0.7 of gestation
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932