Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC.
about
The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix proteinThe mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not alteredHeterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia.Targeting the MYC and PI3K pathways eliminates leukemia-initiating cells in T-cell acute lymphoblastic leukemiaT cell receptor delta gene rearrangements in acute lymphoblastic leukemiaNotch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.Molecular involvement of the pvt-1 locus in a gamma/delta T-cell leukemia bearing a variant t(8;14)(q24;q11) translocation.The epidemiology of childhood leukemia with a focus on birth weight and diet.Mechanisms of transcription factor deregulation in lymphoid cell transformation.T-cell receptor alpha-chain gene is split in a human T-cell leukemia cell line with a t(11;14)(p15;q11).Preferential integration of marker DNA into the chromosomal fragile site at 3p14: an approach to cloning fragile sites.Novel FISH probes designed to detect IGK-MYC and IGL-MYC rearrangements in B-cell lineage malignancy identify a new breakpoint cluster region designated BVR2.The emerging complexity of gene fusions in cancer.Detection of chromosomal translocations in leukemia-lymphoma cells by polymerase chain reaction.Molecular analysis of the t(8;14)(q24;q11) chromosomal breakpoint junctions in the T-cell leukemia line MOLT-16.Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping.Three consecutive primary malignancies in one patient during childhood.
P2860
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P2860
Molecular cloning of the breakpoint junction of a human chromosomal 8;14 translocation involving the T-cell receptor alpha-chain gene and sequences on the 3' side of MYC.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1986
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Molecular cloning of the break ...... quences on the 3' side of MYC.
@en
Molecular cloning of the break ...... quences on the 3' side of MYC.
@nl
type
label
Molecular cloning of the break ...... quences on the 3' side of MYC.
@en
Molecular cloning of the break ...... quences on the 3' side of MYC.
@nl
prefLabel
Molecular cloning of the break ...... quences on the 3' side of MYC.
@en
Molecular cloning of the break ...... quences on the 3' side of MYC.
@nl
P2093
P2860
P356
P1476
Molecular cloning of the break ...... quences on the 3' side of MYC.
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.17.6636
P407
P577
1986-09-01T00:00:00Z