Pten in stromal fibroblasts suppresses mammary epithelial tumours - Wikidata - wikimedia - TriplyDB

Pten in stromal fibroblasts suppresses mammary epithelial tumours

Pten in stromal fibroblasts suppresses mammary epithelial tumours

http://www.wikidata.org/entity/Q37399478

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Targeting the PI3K/Akt cell survival pathway to induce cell death of HIV-1 infected macrophages with alkylphospholipid compounds S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways Report on the use of non-clinical studies in the regulatory evaluation of oncology drugs Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer The Role of the Transcriptional Regulation of Stromal Cells in Chronic Inflammation Genetic instability in the tumor microenvironment: a new look at an old neighbor Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Molecular mechanisms of ETS transcription factor-mediated tumorigenesis Recent developments in myofibroblast biology: paradigms for connective tissue remodeling Role of oxidative stress and the microenvironment in breast cancer development and progression MicroRNA regulation in cancer-associated fibroblasts Interactions between tumor cells and microenvironment in breast cancer: a new opportunity for targeted therapy Tumor stroma as targets for cancer therapy Cancer-associated fibroblasts in digestive tumors Understanding the role of stromal fibroblasts in cancer progression Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer Increased IKKα expression in the basal layer of the epidermis of transgenic mice enhances the malignant potential of skin tumors A secreted PTEN phosphatase that enters cells to alter signaling and survival The PTEN Long N-tail is intrinsically disordered: increased viability for PTEN therapy Cancer evolution and individual susceptibility The Role of PTEN in Tumor Angiogenesis Genetic tools for identifying and manipulating fibroblasts in the mouse Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion Regulation of PTEN stability and activity by Plk3 Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapy The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.Tumors as organs: complex tissues that interface with the entire organism Non-cell-autonomous tumor suppression by p53.Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations.In vivo models in breast cancer research: progress, challenges and future directions.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance Adult stem cels and their niches Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycle MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion.Endogenous antibodies for tumor detection The role of stromal factors in breast tumorigenicity.Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth.DNA methylation in the tumor microenvironment.

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

http://www.wikidata.org/entity/Q37399478

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on October 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Pten in stromal fibroblasts suppresses mammary epithelial tumours

@en

Pten in stromal fibroblasts suppresses mammary epithelial tumours.

@nl

type

label

Pten in stromal fibroblasts suppresses mammary epithelial tumours

@en

Pten in stromal fibroblasts suppresses mammary epithelial tumours.

@nl

prefLabel

Pten in stromal fibroblasts suppresses mammary epithelial tumours

@en

Pten in stromal fibroblasts suppresses mammary epithelial tumours.

@nl

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

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Anand Merchant

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Anthony J Trimboli

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Carmen Z Cantemir-Stone

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Enrico Caserta

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Francois Pepin

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Fu Li

http://www.w3.org/2001/XMLSchema#string

Guo Wei

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Gustavo Leone

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Hui Wang

http://www.w3.org/2001/XMLSchema#string

Jean-Leon Chong

http://www.w3.org/2001/XMLSchema#string

P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant mice

Stromal effects on mammary gland development and breast cancer

Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors

Activation of synovial fibroblasts in rheumatoid arthritis: lack of Expression of the tumour suppressor PTEN at sites of invasive growth and destruction

A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Generalized lacZ expression with the ROSA26 Cre reporter strain

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

Pten is essential for embryonic development and tumour suppression

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1084-1091

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scholarly article

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10.1038/NATURE08486

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7267

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461

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Michael C. Ostrowski

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2009-10-01T00:00:00Z

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38028102

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1042922634

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19847259

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2767301

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