about
Nuclear IGF1R is a transcriptional co-activator of LEF1/TCFTargeting insulin and insulin-like growth factor pathways in epithelial ovarian cancerThe IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approachDefining the pathway to insulin-like growth factor system targeting in cancer.IGF axis and other factors in HPV-related and HPV-unrelated carcinogenesis (review).Treatment with a combination of the ErbB (HER) family blocker afatinib and the IGF-IR inhibitor, NVP-AEW541 induces synergistic growth inhibition of human pancreatic cancer cells.Analysis of cytosine-adenine repeats in P1 promoter region of IGF-1 gene in peripheral blood cells and cervical tissue samples of females with cervical intraepithelial lesions and squamous cervical cancer.A pathobiological role of the insulin receptor in chronic lymphocytic leukemia.Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis.Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.Targeting the insulin-like growth factor receptor: developing biomarkers from gene expression profiling.Molecular and cellular biology of rhabdomyosarcoma.The effects of obesity and obesity-related conditions on colorectal cancer prognosis.Depletion of insulin receptor substrate 2 reverses oncogenic transformation induced by v-src.Endocrine resistance in breast cancer: molecular pathways and rational development of targeted therapies.Insulin-like growth factor 1 stimulation of androgen receptor activity requires β(1A) integrins.Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma.Increased insulin-like growth factor-1 receptor mRNA expression predicts poor survival in immunophenotypes of early breast carcinoma.Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer.[The targets research of non-small cell lung cancer targeted therapy].Coexpression of p-IGF-1R and MMP-7 Modulates Panitumumab and Cetuximab Efficacy in RAS Wild-Type Metastatic Colorectal Cancer Patients.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Customizing the targeting of IGF-1 receptor.
@en
Customizing the targeting of IGF-1 receptor.
@nl
type
label
Customizing the targeting of IGF-1 receptor.
@en
Customizing the targeting of IGF-1 receptor.
@nl
prefLabel
Customizing the targeting of IGF-1 receptor.
@en
Customizing the targeting of IGF-1 receptor.
@nl
P2860
P356
P1433
P1476
Customizing the targeting of IGF-1 receptor.
@en
P2093
Renato Baserga
P2860
P356
10.2217/14796694.5.1.43
P407
P577
2009-02-01T00:00:00Z