Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2 - Wikidata - wikimedia - TriplyDB

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

http://www.wikidata.org/entity/Q24672372

about

microRNA regulation of Wnt signaling pathways in development and disease The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated Proteins Insulin receptor substrate-1 deficiency promotes apoptosis in the putative intestinal crypt stem cell region, limits Apcmin/+ tumors, and regulates Sox9 MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer.Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression IRS1 regulation by Wnt/beta-catenin signaling and varied contribution of IRS1 to the neoplastic phenotype.O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs.Gene expression profile during proliferation and differentiation of rainbow trout adipocyte precursor cells.Insulin receptor substrates (IRSs) and breast tumorigenesis.Sustained c-Jun-NH2-kinase activity promotes epithelial-mesenchymal transition, invasion, and survival of breast cancer cells by regulating extracellular signal-regulated kinase activation.Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.Signal transduction networks in cancer: quantitative parameters influence network topology The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival.MiR-570 inhibits cell proliferation and glucose metabolism by targeting IRS1 and IRS2 in human chronic myelogenous leukemia.The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT Impact of diet-induced obesity on intestinal stem cells: hyperproliferation but impaired intrinsic function that requires insulin/IGF1 Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling.Down-regulation of miR-126 is associated with colorectal cancer cells proliferation, migration and invasion by targeting IRS-1 via the AKT and ERK1/2 signaling pathways The insulin receptor substrate (IRS) proteins: at the intersection of metabolism and cancer.Therapeutic destruction of insulin receptor substrates for cancer treatment.Whole exome sequencing of a single osteosarcoma case--integrative analysis with whole transcriptome RNA-seq data.Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage Differentiation erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines.Type 1 Insulin-Like Growth Factor Receptor/Insulin Receptor Substrate 1 Signaling Confers Pathogenic Activity on Breast Tumor Cells Lacking REST.Association of Bactericidal Dysfunction of Paneth Cells in Streptozocin-Induced Diabetic Mice with Insulin Deficiency Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells.TGFβ/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1.IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer.The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer.Irs2 inactivation suppresses tumor progression in Pten+/- mice.Expression and function of the insulin receptor substrate proteins in cancer Novel insulin receptor substrate 1 and 2 variants in breast and colorectal cancer Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer Customizing the targeting of IGF-1 receptor.IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion.The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.Targeting the insulin-like growth factor receptor: developing biomarkers from gene expression profiling.

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Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

http://www.wikidata.org/entity/Q24672372

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

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name

Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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type

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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prefLabel

Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Molecular and Cellular Biology

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Mammary tumorigenesis and meta ...... r substrate 1 (IRS-1) or IRS-2

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Adrian V Lee

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D Craig Allred

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Darryl L Hadsell

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Hyun-Jung Kim

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Isere Kuiatse

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Jana Divisova

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Nicole A Lawrence

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Ora L Britton

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Robert K Dearth

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Syed Mohsin

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P2860

Association of insulin receptor substrate 1 with simian virus 40 large T antigen

The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas

Differential roles of IRS-1 and SHC signaling pathways in breast cancer cells

Overexpression of insulin receptor substrate-1 emerges early in hepatocarcinogenesis and elicits preneoplastic hepatic glycogenosis

Overexpression of insulin receptor substrate 1 (IRS-1) in the human breast cancer cell line MCF-7 induces loss of estrogen requirements for growth and transformation

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells

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9302-14

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scholarly article

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2872384

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10.1128/MCB.00260-06

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24

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26

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6763847

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17030631

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1698542

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