Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.
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Scientific rationale for the use of alpha-adrenergic agonists and glucocorticoids in the therapy of pediatric stridor.β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4DBeta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.Constitutively active signaling by the G protein βγ-subunit mediates intrinsically increased phosphodiesterase-4 activity in human asthmatic airway smooth muscle cells.Salmeterol Efficacy and Bias in the Activation and Kinase-Mediated Desensitization of β2-Adrenergic Receptors.G Protein βγ-subunit signaling mediates airway hyperresponsiveness and inflammation in allergic asthma.Large-scale profiling of signalling pathways reveals an asthma specific signature in bronchial smooth muscle cellsEpigenetic alterations by DNA methylation in house dust mite-induced airway hyperresponsiveness.Current concepts on the use of glucocorticosteroids and beta-2-adrenoreceptor agonists to treat childhood asthmaCan β2-adrenoceptor agonists, anticholinergic drugs, and theophylline contribute to the control of pulmonary inflammation and emphysema in COPD?The pivotal role of airway smooth muscle in asthma pathophysiologyBeta-Adrenergic AgonistsMechanism of glucocorticoid protection of airway smooth muscle from proasthmatic effects of long-acting beta2-adrenoceptor agonist exposure.Rosiglitazone reverses salbutamol-induced β(2) -adrenoceptor tolerance in airway smooth muscleCyclic Adenosine Monophosphate-Mediated Enhancement of Vascular Endothelial Growth Factor Released by Differentiated Human Monocytic Cells: The Role of Protein Kinase A.PGE 2 desensitizes β -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4.Future bronchodilator therapy: a bitter pill to swallow?G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands.Emerging inhaled long-acting beta-2 adrenoceptor agonists for the treatment of COPD.Compartmentalized cAMP responses to prostaglandin EP2 receptor activation in human airway smooth muscle cells.Polygonum aviculare L. extract and quercetin attenuate contraction in airway smooth muscle.
P2860
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P2860
Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 07 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@en
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@nl
type
label
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@en
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@nl
prefLabel
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@en
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@nl
P2093
P2860
P1476
Mechanism regulating proasthma ...... ation in airway smooth muscle.
@en
P2093
Gustavo Nino
Judith S Grunstein
Michael M Grunstein
P2860
P304
P356
10.1152/AJPLUNG.00079.2009
P577
2009-08-07T00:00:00Z