Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
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O(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problemsContemporary murine models in preclinical astrocytoma drug developmentA nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.Restoration of sensitivity in chemo-resistant glioma cells by cold atmospheric plasma.Temozolomide added to whole brain radiotherapy in patients with multiple brain metastases of non-small-cell lung cancer: a multicentric Austrian phase II study.Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models.Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS production.Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chainRedox-responsive magnetic nanoparticle for targeted convection-enhanced delivery of O6-benzylguanine to brain tumorsHypofractionated intensity modulated radiotherapy with temozolomide in newly diagnosed glioblastoma multiformeEstablishment, maintenance and in vitro and in vivo applications of primary human glioblastoma multiforme (GBM) xenograft models for translational biology studies and drug discovery.Expression of CD74 in high grade gliomas: a potential role in temozolomide resistance.Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patientsPreclinical evaluation of a genetically engineered herpes simplex virus expressing interleukin-12p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells.Treatment of recurrent metastatic uterine leiomyosarcoma of the spine: a multimodality approach using resection, radiosurgery, and chemotherapy.Patient-Derived Xenografts as a Model System for Radiation ResearchEfficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models.Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of GlioblastomaQuantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma.Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts.Network Modeling Identifies Patient-specific Pathways in Glioblastoma.MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma.Radiation sensitivity and sensitization in melanoma.Harnessing the cell death pathway for targeted cancer treatment.Glioblastoma, a brief review of history, molecular genetics, animal models and novel therapeutic strategies.Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme.Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth.Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics.Convertible MRI contrast: Sensing the delivery and release of anti-glioma nano-drugs.Temozolomide nanoparticles for targeted glioblastoma therapy.Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma.Integrins and p53 pathways in glioblastoma resistance to temozolomide.Toxicity and survival in primary glioblastoma patients treated with concomitant plus adjuvant temozolomide versus adjuvant temozolomide: results of a single-institution, retrospective, matched-pair analysis.Microtubule-targeting agents can sensitize cancer cells to ionizing radiation by an interphase-based mechanism.LPA signaling is regulated through the primary cilium: a novel target in glioblastoma.Postoperative neoadjuvant temozolomide before radiotherapy versus standard radiotherapy in patients 60 years or younger with anaplastic astrocytoma or glioblastoma: a randomized trial.
P2860
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P2860
Radiosensitizing effects of temozolomide observed in vivo only in a subset of O6-methylguanine-DNA methyltransferase methylated glioblastoma multiforme xenografts.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Radiosensitizing effects of te ...... lastoma multiforme xenografts.
@en
Radiosensitizing effects of te ...... lastoma multiforme xenografts.
@nl
type
label
Radiosensitizing effects of te ...... lastoma multiforme xenografts.
@en
Radiosensitizing effects of te ...... lastoma multiforme xenografts.
@nl
prefLabel
Radiosensitizing effects of te ...... lastoma multiforme xenografts.
@en
Radiosensitizing effects of te ...... lastoma multiforme xenografts.
@nl
P2093
P2860
P1476
Radiosensitizing effects of te ...... blastoma multiforme xenografts
@en
P2093
Ann C Mladek
Brett L Carlson
C David James
Caterina Giannini
Gaspar J Kitange
Jann N Sarkaria
Mark A Schroeder
Patrick T Grogan
Paul A Decker
Wenting Wu
P2860
P304
P356
10.1016/J.IJROBP.2009.04.026
P407
P577
2009-09-01T00:00:00Z