MUC1 oncoprotein is a druggable target in human prostate cancer cells.
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Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPHMucins in cancer: function, prognosis and therapyProstate cancer relevant antigens and enzymes for targeted drug deliveryThe Role of Galectin-1 in Cancer Progression, and Synthetic Multivalent Systems for the Study of Galectin-1Intracellular Targeting of the Oncogenic MUC1-C Protein with a Novel GO-203 Nanoparticle FormulationOrigin of anti-tumor activity of the cysteine-containing GO peptides and further optimization of their cytotoxic properties.Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.MUCIN 1 ONCOPROTEIN EXPRESSION IS SUPPRESSED BY THE miR-125b ONCOMIRProtein mislocalization: mechanisms, functions and clinical applications in cancer.EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1.MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization.Terminal differentiation of chronic myelogenous leukemia cells is induced by targeting of the MUC1-C oncoprotein.MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells.MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cellsMolecular Validation of PACE4 as a Target in Prostate CancerTransmembrane mucins as novel therapeutic targetsAutophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cellsMUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer.Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition.Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.Comparison of cytotoxic T lymphocyte responses against pancreatic cancer induced by dendritic cells transfected with total tumor RNA and fusion hybrided with tumor cell.Ki67-BCL2 index in prognosis of malignant peritoneal mesothelioma.Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.Mucins in pancreatic cancer and its microenvironment.MUC1 (CD227): a multi-tasked molecule.Chemotherapy treatment induces an increase of autophagy in the luminal breast cancer cell MCF7, but not in the triple-negative MDA-MB231.Monoclonal antibody conjugated magnetic nanoparticles could target MUC-1-positive cells in vitro but not in vivo.Human dendritic cells transfected with amplified MUC1 mRNA stimulate cytotoxic T lymphocyte responses against pancreatic cancer in vitro.Androgen receptor regulates expression of the MUC1-C oncoprotein in human prostate cancer cellsGlycodendrimers: tools to explore multivalent galectin-1 interactionsImplication of Soluble Forms of Cell Adhesion Molecules in Infectious Disease and Tumor: Insights from Transgenic Animal Models.MUC1: The First Respiratory Mucin with an Anti-Inflammatory Function.
P2860
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P2860
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@en
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@nl
type
label
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@en
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@nl
prefLabel
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@en
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@nl
P2093
P2860
P1476
MUC1 oncoprotein is a druggable target in human prostate cancer cells.
@en
P2093
Deepak Raina
Donald Kufe
Glenn Bubley
Hasan Rajabi
Maya Datt Joshi
Rehan Ahmad
Surender Kharbanda
P2860
P304
P356
10.1158/1535-7163.MCT-09-0646
P577
2009-11-03T00:00:00Z