MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop. - Wikidata - wikimedia - TriplyDB

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

http://www.wikidata.org/entity/Q34759460

about

MUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cells MUC1 and MUC4: switching the emphasis from large to small Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells Enteroaggregative Escherichia coli Adherence Fimbriae Drive Inflammatory Cell Recruitment via Interactions with Epithelial MUC1.Cytotoxic efficacy of a novel dinuclear platinum(II) complex used with anti-MUC1 in human breast cancer cells.Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.MUC1: a multifaceted oncoprotein with a key role in cancer progression.Towards a quantitative understanding of the MITF-PIAS3-STAT3 connection MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization.Targeting the oncogenic MUC1-C protein inhibits mutant EGFR-mediated signaling and survival in non-small cell lung cancer cells MUC1 protein induces urokinase-type plasminogen activator (uPA) by forming a complex with NF-κB p65 transcription factor and binding to the uPA promoter, leading to enhanced invasiveness of cancer cells.The role of the small GTPase Rab31 in cancer.Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells.15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway.A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domain MUC1-C oncoprotein induces TCF7L2 transcription factor activation and promotes cyclin D1 expression in human breast cancer cells.Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells MUC1-C activates the TAK1 inflammatory pathway in colon cancer The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.Muc-1 promotes migration and invasion of oral squamous cell carcinoma cells via PI3K-Akt signaling MUC1 drives c-Met-dependent migration and scattering.Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.Oncogenic MUC1-C promotes tamoxifen resistance in human breast cancer.MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial-mesenchymal transition.MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cells The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression.STAT3 Target Genes Relevant to Human Cancers.Genetic regulation of MUC1 expression by Helicobacter pylori in gastric cancer cells.Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells.Bone marrow stroma protects myeloma cells from cytotoxic damage via induction of the oncoprotein MUC1.β2-AR signaling controls trastuzumab resistance-dependent pathway.Natural Withanolides in the Treatment of Chronic Diseases.MUC1-C Oncoprotein Integrates a Program of EMT, Epigenetic Reprogramming and Immune Evasion in Human Carcinomas.Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.MUC1 inhibition leads to decrease in PD-L1 levels via upregulation of miRNAs.

P2860

Q24336566-A89FD39A-BA98-47D8-BFE3-486F334E361B Q24599141-AA379DE8-E326-4474-8CB0-E53D2435EA87 Q28547180-C536BBC8-E0B0-4A56-9CE0-D7D81129C6A2 Q28727361-6892045F-03C9-4E46-A816-F4857DF614BD Q30252193-6CF150D4-F071-46EA-9276-C33601BF7822 Q33741303-709DA881-EB48-44F6-8944-123C0059C1D4 Q33827824-EDE1873C-8F0B-47C4-A4BA-B567F3A94E09 Q33880143-A34D58E4-796A-47FD-9BD1-6A2301C075C0 Q34153534-7C908C29-1C19-4233-B88A-E22F1BC2BDD7 Q34389169-BA77937D-5F8D-44B2-A43D-4AEA88F079DB Q34449722-BDF12AAC-BA9B-4DDB-81C2-3D977EEE07E9 Q34737810-EFA0E5F6-EC75-456D-A4A6-A8A4B2177385 Q34885255-8596812F-DF65-4315-B38C-9D60016D9D9B Q34970672-ED8A4604-EA70-46DF-99C3-727D43C760BA Q35660062-A2AECA64-F669-4996-9379-A1904F8B5C1A Q35754887-D4C24D1A-6330-43BB-8BD3-EC6576BE68B2 Q35879924-EF02BD7D-C683-49FA-B75C-985E42B6D7A5 Q35888913-50728B68-4017-4723-B8E3-3B3B94FB9F08 Q35931767-4E09DAC9-ABAC-4192-9572-35A85CDE8513 Q36033113-1CCD9789-A71F-41F2-AE64-58D95598A990 Q36146986-8B1E8F6A-41A6-48C4-BDC3-9E17F13F2E9C Q36237322-1DC1B1E5-A56E-4149-80ED-36A3D98D4E9A Q36261375-139DE935-FEB1-4D37-B022-4BAE4C625A5B Q36484469-B7CD24FC-2D1E-4F33-A90E-5BBC15AD4E58 Q36737884-CBCA7D05-474E-48D2-8DB7-306665CAC247 Q36753508-719197B8-E403-4B1F-B6B9-C765E12FA9C3 Q37022006-D45AB90A-C2D5-4D6B-9143-65C04C330D4A Q37038731-CF0F7478-B359-4B5A-ABAE-F4100C87FB2A Q37198652-61E6CF43-D60E-41F3-A45C-991EAF8F5637 Q37535249-D10332EB-8378-4BFB-8451-7DCEAC04C9D1 Q37695311-2EEE6D87-21C1-4A85-9F1E-CA628A15CF71 Q38205362-0B6C9F94-44B0-49E5-A4FB-637BA9D613AC Q38473047-BF456ECB-1B46-428F-8659-54445F288748 Q38686618-3D3D2BD0-C585-4C3C-BDA2-262044DF87DA Q38720340-8CBE07E9-E745-42CE-BCF6-38ECC4BF3DC3 Q38896403-68788FAE-E873-4AA4-86F1-C4559E646C52 Q38965226-EF447F23-8C94-4C88-84EC-C1FE3344A041 Q39182659-4ED817BA-976A-4DD5-B111-646843CBF804 Q42376411-E4D548C5-9CC4-415C-882A-60570D089C84 Q47726182-A10276F0-A6A2-4AF4-AD42-BE689A9DD51A

P2860

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

http://www.wikidata.org/entity/Q34759460

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@ast

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@en

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@nl

type

label

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@ast

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@en

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@nl

prefLabel

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@ast

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@en

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@nl

P1433

Q34759460-4971A465-8B07-4BBB-8378-9CE2A48DFB44

P1476

Q34759460-92515606-1D9D-4CF3-858B-79AEFA10BE70

P2093

Q34759460-20B9A793-A06F-465C-B838-502B1B21379A

Q34759460-25B2C395-9500-4CA9-8A84-7CF161B001AE

Q34759460-3BE78078-0EA7-45CA-BF3B-3C475C3EF290

Q34759460-458A424E-9432-4294-B73E-43280B18A462

Q34759460-5E72C446-F6D7-4D05-8DC0-9B04B662A83C

Q34759460-8097A234-69FA-4B6A-B55C-DAD60F1105C0

Q34759460-95A7FBAE-EF55-48A6-B8EA-8DAF2759C054

Q34759460-A1A8E96E-B3D2-4C68-BE1B-9B505CFCF861

Q34759460-E50478CA-B9AC-4BFD-B461-5182F0955511

P2860

Q34759460-00A32316-02B6-411F-9926-AD1F422A2F88

Q34759460-024556D2-EC71-488C-9342-0F0C43617C8E

Q34759460-05D21B7D-6565-46B9-8A8E-455207B76B03

Q34759460-10A0A117-B3EC-4F4C-AF41-0266623BB930

Q34759460-12E5E6A2-2FB2-4F02-AAD8-19BA2DF2C0E6

Q34759460-170E5C5A-2043-45C3-B89B-98AC4893DEEC

Q34759460-19528008-366D-40E3-AB83-B7C83CA82DE3

Q34759460-1FA6DA9D-0B5C-4E59-8C19-99AAEB0FBE04

Q34759460-27D2B1AA-7D15-4CCF-A097-B7C049A76604

Q34759460-2F6503C6-8F58-4878-8230-5A006CF8194C

P304

Q34759460-473CFF48-8864-4986-9807-F9C58C5D94FD

P31

Q34759460-10657E4E-A739-4C65-90AD-EAD540328810

P356

Q34759460-87762EE6-9877-46C3-B097-3CA2A324C73C

P433

Q34759460-B7361CC0-FDE3-41B2-ADF5-C6B0045ECF1F

P478

Q34759460-F662594B-A167-4747-B77F-8599F77506D0

P577

Q34759460-EEB9391D-4360-4193-8BAA-16ADB850A552

P5875

Q34759460-E17EA43D-60C2-433F-B050-9E336D488872

P698

Q34759460-BE4D3ACD-D40C-4826-B164-DBDCA7CD1920

P932

Q34759460-8BBB4DA3-963B-45C1-B149-4C1D4987019E

P356

SCISIGNAL.2001426

P1433

Science Signaling

P1476

MUC1-C oncoprotein promotes STAT3 activation in an autoinductive regulatory loop.

@en

P2093

Baldev Vasir

http://www.w3.org/2001/XMLSchema#string

Donald Kufe

http://www.w3.org/2001/XMLSchema#string

Hasan Rajabi

http://www.w3.org/2001/XMLSchema#string

Maroof Alam

http://www.w3.org/2001/XMLSchema#string

Maya Datt Joshi

http://www.w3.org/2001/XMLSchema#string

Michio Kosugi

http://www.w3.org/2001/XMLSchema#string

Rehan Ahmad

http://www.w3.org/2001/XMLSchema#string

Surender Kharbanda

http://www.w3.org/2001/XMLSchema#string

Takeshi Kawano

http://www.w3.org/2001/XMLSchema#string

P2860

Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response

Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors.

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

Interacting regions in Stat3 and c-Jun that participate in cooperative transcriptional activation

Mucins in cancer: function, prognosis and therapy

A Stat3-interacting protein (StIP1) regulates cytokine signal transduction

A road map for those who don't know JAK-STAT

MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90

MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin

Cell-associated episialin is a complex containing two proteins derived from a common precursor

P304

ra9

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1126/SCISIGNAL.2001426

http://www.w3.org/2001/XMLSchema#string

P433

160

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P577

2011-02-15T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49839872

http://www.w3.org/2001/XMLSchema#string

P698

21325207

http://www.w3.org/2001/XMLSchema#string

P932

3070357

http://www.w3.org/2001/XMLSchema#string