Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombination.
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A properly configured ring structure is critical for the function of the mitochondrial DNA recombination protein, Mgm101.Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination.A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101.Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2RecO protein initiates DNA recombination and strand annealing through two alternative DNA binding mechanisms.Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability.Rad52/Rad59-dependent recombination as a means to rectify faulty Okazaki fragment processing.Timing is everything: cell cycle control of Rad52The budding yeast Mei5-Sae3 complex interacts with Rad51 and preferentially binds a DNA fork structure.Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiaeHomologous recombination and its regulationPro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.SUMOylation of Rad52-Rad59 synergistically change the outcome of mitotic recombination.Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA RecombinationEukaryotic DNA Polymerases in Homologous Recombination.Enhancement of gene targeting in human cells by intranuclear permeation of the Saccharomyces cerevisiae Rad52 proteinMutational analysis of Brh2 reveals requirements for compensating mediator functions.Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination.Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq.Homology Requirements and Competition between Gene Conversion and Break-Induced Replication during Double-Strand Break Repair.
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Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombination.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role of the Rad52 amino-termin ...... e in homologous recombination.
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Role of the Rad52 amino-termin ...... e in homologous recombination.
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type
label
Role of the Rad52 amino-termin ...... e in homologous recombination.
@en
Role of the Rad52 amino-termin ...... e in homologous recombination.
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prefLabel
Role of the Rad52 amino-termin ...... e in homologous recombination.
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Role of the Rad52 amino-termin ...... e in homologous recombination.
@nl
P2093
P2860
P356
P1476
Role of the Rad52 amino-termin ...... e in homologous recombination.
@en
P2093
Changhyun Seong
Patrick Sung
Swee C L Hallwyl
Uffe Mortensen
P2860
P304
33275-33284
P356
10.1074/JBC.M109.057752
P407
P577
2009-10-06T00:00:00Z