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Antibody-mediated xenograft injury: mechanisms and protective strategies.

Antibody-mediated xenograft injury: mechanisms and protective strategies.

http://www.wikidata.org/entity/Q37450148

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Current status of xenotransplantation and prospects for clinical application Expression of human CD46 modulates inflammation associated with GalTKO lung xenograft injury Double transgenic pigs with combined expression of human α1,2-fucosyltransferase and α-galactosidase designed to avoid hyperacute xenograft rejection Transgenic pigs designed to express human α-galactosidase to avoid humoral xenograft rejection Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing.Lung xenotransplantation: recent progress and current status.No evidence for αGal epitope transfer from media containing FCS onto human endothelial cells in culture.Transplantable bioartificial pancreas devices: current status and future prospects.Lung xenotransplantation: a review Decellularized GGTA1-KO pig heart valves do not bind preformed human xenoantibodies.Absence of Gal epitope prolongs survival of swine lungs in an ex vivo model of hyperacute rejection.Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model

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P2860

Antibody-mediated xenograft injury: mechanisms and protective strategies.

http://www.wikidata.org/entity/Q37450148

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 17 April 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Antibody-mediated xenograft injury: mechanisms and protective strategies.

@en

Antibody-mediated xenograft injury: mechanisms and protective strategies.

@nl

type

label

Antibody-mediated xenograft injury: mechanisms and protective strategies.

@en

Antibody-mediated xenograft injury: mechanisms and protective strategies.

@nl

prefLabel

Antibody-mediated xenograft injury: mechanisms and protective strategies.

@en

Antibody-mediated xenograft injury: mechanisms and protective strategies.

@nl

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J.TRIM.2009.03.008

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Transplant Immunology

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Antibody-mediated xenograft injury: mechanisms and protective strategies.

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Richard N Pierson

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P2860

Acute vascular rejection of xenografts: roles of natural and elicited xenoreactive antibodies in activation of vascular endothelial cells and induction of procoagulant activity.

Renal xenografts from triple-transgenic pigs are not hyperacutely rejected but cause coagulopathy in non-immunosuppressed baboons.

Molecular incompatibilities in hemostasis between swine and men--impact on xenografting.

Co-stimulation blockade targeting CD154 and CD28/B7 modulates the induced antibody response after a pig-to-baboon cardiac xenograft.

Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenografts.

Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation.

Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations.

Venular thrombosis is the key event in the pathogenesis of antibody-mediated cardiac rejection.

Production of alpha 1,3-galactosyltransferase-deficient pigs.

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys.

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65-69

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10.1016/J.TRIM.2009.03.008

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2

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