Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase. - Wikidata - wikimedia - TriplyDB

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.

Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.

http://www.wikidata.org/entity/Q37453462

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Can follicular helper T cells be targeted to improve vaccine efficacy?Signaling in T cells - is anything the m(a)TOR with the picture(s)?Life of T follicular helper cells FOXO transcription factors throughout T cell biology Follicular Helper T Cells in Systemic Lupus Erythematosus: Why Should They Be Considered as Interesting Therapeutic Targets?Regulators of Tfh Cell Differentiation ICOS Co-Stimulation: Friend or Foe?The differential expression of IL-4 and IL-13 and its impact on type-2 immunity Signaling by the phosphoinositide 3-kinase family in immune cells The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses.Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial.T-cell subsets in the germinal center.Molecular control of Tfh-cell differentiation by Roquin family proteins.Anti-chlamydial Th17 responses are controlled by the inducible costimulator partially through phosphoinositide 3-kinase signaling The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cells.CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement.Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice ICOS regulates the generation and function of human CD4+ Treg in a CTLA-4 dependent manner.ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development.A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells.Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.STAT5 is a potent negative regulator of TFH cell differentiation.Increased circulating follicular helper T cells with decreased programmed death-1 in chronic renal allograft rejection.PI3Ks in lymphocyte signaling and development IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response The origins, function, and regulation of T follicular helper cells miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.Phenotypic Tfh development promoted by CXCR5-controlled re-localization and IL-6 from radiation-resistant cells The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases PI3K signalling in B- and T-lymphocytes: new developments and therapeutic advances Phenotype and function of CXCR5+CD45RA-CD4+ T cells were altered in HBV-related hepatocellular carcinoma and elevated serum CXCL13 predicted better prognosis.A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

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Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase.

http://www.wikidata.org/entity/Q37453462

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Inducible costimulator promote ...... ugh phosphoinositide 3-kinase.

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Inducible costimulator promote ...... ugh phosphoinositide 3-kinase.

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type

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Inducible costimulator promote ...... ugh phosphoinositide 3-kinase.

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Inducible costimulator promote ...... ugh phosphoinositide 3-kinase.

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Inducible costimulator promote ...... ough phosphoinositide 3-kinase

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Jijun Shang

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Jongseon Choe

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Minghong Xu

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Tak W Mak

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Youngshil Pak

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P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

ICOS co-stimulatory receptor is essential for T-cell activation and function

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

The B7 family revisited

Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

Bcl6 mediates the development of T follicular helper cells

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

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Woong-Kyung Suh

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38091085

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2787139

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