Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
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Mechanisms behind functional avidity maturation in T cellsEx vivo enzymatic treatment of aged CD4 T cells restores cognate T cell helper function and enhances antibody production in miceDynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell ActivationAction and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseCell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand RecognitionAutoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsLigand mobility modulates immunological synapse formation and T cell activationProgrammed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.A proteomic view at T cell costimulationTCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection.Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.Line tension and stability of domains in cell-adhesion zones mediated by long and short receptor-ligand complexesSpatial association of signaling proteins and F-actin effects on cluster assembly analyzed via photoactivation localization microscopy in T cellsMechanisms of costimulation.Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse.HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.CD80 and CD86 differentially regulate mechanical interactions of T-cells with antigen-presenting dendritic cells and B-cells.Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cellsRapid perturbation in viremia levels drives increases in functional avidity of HIV-specific CD8 T cells.On the issue of peptide recognition in T cell development.A microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays.In and out of the bull's eye: protein kinase Cs in the immunological synapse.Spatial organization and signal transduction at intercellular junctionsThe network of receptors characterize B cell receptor micro- and macroclustering in a Monte Carlo model.T cell activation is determined by the number of presented antigens.Tethering of intercellular adhesion molecule on target cells is required for LFA-1-dependent NK cell adhesion and granule polarization.Signaling microdomains in T cells.T cell receptor signaling kinetics takes the stage.Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 familyFunctional avidity: a measure to predict the efficacy of effector T cells?Microscopy approaches to investigate protein dynamics and lipid organization.Cutting edge: A role for inside-out signaling in TCR regulation of CD28 ligand bindingIntraflagellar transport: a new player at the immune synapse.Overlooked Mechanisms in Type 1 Diabetes Etiology: How Unique Costimulatory Molecules Contribute to DiabetogenesisControlling T-Cell Activation with Synthetic Dendritic Cells Using the Multivalency Effect.Cell cycle arrest caused by MEK/ERK signaling is a mechanism for suppressing growth of antigen-hyperstimulated effector T cells.Janus Nanoparticles for T Cell Activation: Clustering Ligands to Enhance Stimulation.CD40-CD40L cross-talk drives fascin expression in dendritic cells for efficient antigen presentation to CD4+ T cells.Immunological Synapse Predicts Effectiveness of Chimeric Antigen Receptor Cells.Dephosphorylation of Bcl-10 by calcineurin is essential for canonical NF-κB activation in Th cells.
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P2860
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@en
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@nl
type
label
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@en
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@nl
prefLabel
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@en
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@nl
P2860
P1476
Dynamic regulation of T-cell costimulation through TCR-CD28 microclusters.
@en
P2093
Tadashi Yokosuka
P2860
P356
10.1111/J.1600-065X.2009.00779.X
P577
2009-05-01T00:00:00Z