Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting
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T cells and their eons-old obsession with MHCDeletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell developmentMouse homologues of human hereditary disease.Activated pulmonary macrophages are insufficient for resistance against Pneumocystis carinii.Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient miceCharacterization of immature thymocyte lines derived from T-cell receptor or recombination activating gene 1 and p53 double mutant mice.Genomic deletions of the Drosophila melanogaster Hsp70 genesThe effects of terminal heterologies on gene targeting by insertion vectors in embryonic stem cells.Naturally acquired Pneumocystis carinii pneumonia in gene disruption mutant mice: roles of distinct T-cell populations in infectionBi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis.Influence of a CTCF-Dependent Insulator on Multiple Aspects of Enhancer-Mediated Chromatin OrganizationAn ectopic CTCF-dependent transcriptional insulator influences the choice of Vβ gene segments for VDJ recombination at TCRβ locus.Mice cloned from embryonic stem cellsId3 restricts the developmental potential of gamma delta lineage during thymopoiesis.Protective role of gammadelta T cells in spontaneous ocular inflammationTargeting of the T-cell receptor zeta-chain gene in embryonic stem cells: strategies for generating multiple mutations in a single gene.Mast cells are required for full expression of allergen/SEB-induced skin inflammation.The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy.Overview: generation of gene knockout mice.Immunoglobulin gene transcription ceases upon deletion of a distant enhancer.Establishment and growth responses of Nile tilapia embryonic stem-like cell lines under feeder-free condition.Cutting Edge: Dual TCRα Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation.Embryonic stem cell gene targeting using bacteriophage lambda vectors generated by phage-plasmid recombination.A targeted mutation at the T-cell receptor alpha/delta locus impairs T-cell development and reveals the presence of the nearby antiapoptosis gene Dad1.Lymphocyte development and function in T-cell receptor and RAG-1 mutant mice.Targeting of the Gi2 alpha gene in ES cells with replacement and insertion vectors.Targeting frequency for deletion vectors in embryonic stem cells.Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.Self tolerance to T cell receptor V beta sequences.The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor.Using knockout and transgenic mice to study neurophysiology and behavior.Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response
P2860
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P2860
Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on April 1991
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Creation of a large genomic de ...... c stem cells by gene targeting
@en
Creation of a large genomic de ...... stem cells by gene targeting.
@nl
type
label
Creation of a large genomic de ...... c stem cells by gene targeting
@en
Creation of a large genomic de ...... stem cells by gene targeting.
@nl
prefLabel
Creation of a large genomic de ...... c stem cells by gene targeting
@en
Creation of a large genomic de ...... stem cells by gene targeting.
@nl
P2093
P2860
P356
P1476
Creation of a large genomic de ...... c stem cells by gene targeting
@en
P2093
Mombaerts P
Tonegawa S
P2860
P304
P356
10.1073/PNAS.88.8.3084
P407
P577
1991-04-01T00:00:00Z