Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice - Wikidata - wikimedia - TriplyDB

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice

http://www.wikidata.org/entity/Q33911256

about

The germinal center antibody response in health and disease B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity Restoring the balance: immunotherapeutic combinations for autoimmune disease Altered B cell signalling in autoimmunity.B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers.Innate immune programing by endotoxin and its pathological consequences TLR7 influences germinal center selection in murine SLE.The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice Toll-like receptors: potential targets for lupus treatment Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels.Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus B-cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott-Aldrich syndrome.The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity.B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice.LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity.Toll-Like Receptor Ligand-Based Vaccine Adjuvants Require Intact MyD88 Signaling in Antigen-Presenting Cells for Germinal Center Formation and Antibody Production.Toll-like receptors and B cells: functions and mechanisms.Signaling mechanisms regulating B-lymphocyte activation and tolerance.Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis.TLR7/TLR9- and B Cell Receptor-Signaling Crosstalk: Promotion of Potentially Dangerous B Cells.Germinal centers and autoimmune disease in humans and mice.Functions of Murine Dendritic Cells.Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity.The Nexus of Stem Cell-Derived Beta-Cells and Genome Engineering.Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.Deficiency in IRAK4 activity attenuates manifestations of murine Lupus.Spontaneous germinal centers and autoimmunity.Basophils contribute to pristane-induced Lupus-like nephritis model.Adaptive Immunity and Metabolic Health: Harmony Becomes Dissonant in Obesity and Aging.Proteomic analysis reveals distinctive protein profiles involved in CD8+ T cell-mediated murine autoimmune cholangitis.IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate.Toll-like receptors in lupus nephritis.Lyn, Lupus, and (B) Lymphocytes, a Lesson on the Critical Balance of Kinase Signaling in Immunity.Short-term MyD88 inhibition ameliorates cardiac graft rejection and promotes donor-specific hyporesponsiveness of skin grafts in mice.Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus.Multilayer Control of B Cell Activation by the B Cell Antigen Receptor: Following Themes Initiated With Bill Paul.MyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling

P2860

Q26745929-EF5CF04E-EDA7-4432-A4DF-EB5562447C26 Q26996644-8377786D-0784-4927-9982-A2FCB305D4F4 Q27024588-D3D86998-A8D9-42A6-8DCE-30C051F99E80 Q33555986-EE6DD128-0B13-41B8-8D16-DEBF3AF6D26C Q33924642-47768384-9B51-442A-92D2-9F5CD7D26C26 Q34364711-154D4EFB-C4BB-411A-874C-5E57D5DAF1D0 Q34841012-5EB43732-A63D-4C00-AA8B-9575D35F9EAD Q35202579-EEDCDC64-0A0C-4C24-A3D4-B90BA1278A5D Q35538362-DCFDAFB0-6FD8-4884-A8EC-21459055DDE4 Q35848152-29764C9F-F93D-4016-8454-D44F39B6B3B9 Q35988682-C4D97ECE-E9A7-4F64-997F-882B3E64FB41 Q36196097-3DDE4703-2FE4-47DC-A21E-B15040EBC5AA Q36371940-30A3C79F-5923-4ADC-8C47-B27F26E31056 Q36499489-971B3367-AEC3-4E96-ADAA-A05C75D3140B Q36863144-FAFBB98C-90F8-4BE7-BFA4-D45A5B84E505 Q36863150-6580DC10-372E-461C-9A2F-199EA767BD4C Q36965870-D1BCB5BA-9E7F-4A81-8443-4B53E87B7C2F Q37381383-D0649425-94DF-4324-9234-B736CC85C468 Q37677962-9E97D903-3FB0-432F-B1D4-5B9AE3A90B60 Q38213432-6EAC9587-3620-4FA2-82BB-11A108E12F18 Q38334794-F857FD19-5BEB-4497-BC13-4167C3121E7E Q38396871-E49DB15B-FCB5-4EC5-9F1B-01B0D96D232B Q38656329-86BFB2DE-07E3-45B3-98D1-BD79CCE994D9 Q38937343-1D792B6A-6278-4EB6-A26A-6AE5F012A0F4 Q38985483-2A8C6336-1628-4E3F-BB7B-334979250624 Q39272758-F936DB44-730D-4856-8E33-DBF83FA9752A Q39386163-1A7AF6AA-0AF5-46C2-BE13-4B17AC9595B8 Q40173384-8B940FBF-C180-4B53-8ADB-919B64BF8F6E Q40293670-7345EC4F-B0E5-44EF-ACFD-98CB3B79A172 Q40343247-31209D52-2068-4EF2-9731-13CE91ABE27F Q41367448-D27DDDAE-F3FF-4737-B45D-93A5AFAE0A25 Q47670316-FA79B643-1008-44ED-9A3E-E31011D638F0 Q48156075-857D1C83-B0CB-48A8-965C-5A1A78AF4E67 Q50420195-BC4C7A84-14E1-4D17-AE9C-7E881A803B12 Q52323268-7DFF1FFE-B797-4FC4-96AD-48FDD9B97CFE Q52726230-C9804F56-1682-4853-9D5B-78FB682C03C0 Q54151722-AE8A963F-3376-4875-8845-6E9633E5199E Q55266542-1CA81409-ADF4-4184-B706-8707B0A79F7B Q55418527-F2382DD8-B8D3-4271-84F6-1015B57DBF58 Q58700279-0005C720-A40E-420B-9D7B-5793859A3753

P2860

Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice

http://www.wikidata.org/entity/Q33911256

description

2013 nî lūn-bûn

@nan

2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@ast

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@en

type

label

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@ast

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@en

prefLabel

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@ast

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@en

P1433

Q33911256-7EAD8269-C248-4C56-9A86-95BA6665303A

P1476

Q33911256-FF9D092B-CC57-4488-8311-2792526FEF1B

P2093

Q33911256-1D6BA5F1-4D0C-46B2-90D7-3B6641B4AC20

Q33911256-37AF10C7-BDBC-4748-BFD7-7BE99E3C0DA0

Q33911256-42285ED4-1F79-46A2-80D8-DCF480F60748

Q33911256-49EDD810-6A7B-4E62-B5DF-3A3E2DCF187B

Q33911256-5E0C27E6-B6B6-4AB8-98B2-BE8A6C19312A

Q33911256-68E275A0-2971-47BC-B5F3-911C40453F7A

Q33911256-9CFEBE0B-FF50-4040-A057-FAF28992DF47

Q33911256-D7D36C92-DF59-490D-B3C9-56CB0E377D88

P2860

Q33911256-004F5D06-7E3D-4874-BD79-9A267E2700E7

Q33911256-043CFBC4-C06E-4217-9122-71C34F1D49FE

Q33911256-0FFAF194-B395-4D8D-ACD6-7B82834D3166

Q33911256-166E4CA5-001F-4611-B9D3-3E4687534260

Q33911256-1C5B0505-4440-4CDA-96BA-D1946018BD6A

Q33911256-1EDE9C8A-2E73-4744-AE38-AB76B56C2A15

Q33911256-21270D67-5DFE-49E3-9387-45AD83BFC9AC

Q33911256-213C53AA-32DF-48F0-8612-69D5544CC3C0

Q33911256-21599B9F-6056-412F-B0BC-46A6B458CB33

Q33911256-2E5919FB-20AE-4891-9B05-1DE387B0BC50

P304

Q33911256-A25107FA-BA3F-49E4-A727-48495503E27D

P31

Q33911256-3ADF19B5-B418-4407-82CE-01ACFFE76C9D

P356

Q33911256-E83CDCA7-6F92-42F8-ADC1-2A04F558A3AE

P407

Q33911256-A4BF50F1-EDE5-444E-A9AE-1C6D0AF7F49F

P433

Q33911256-2F67E813-C557-4A65-BED1-C646C74C8AD1

P478

Q33911256-339F255F-FB6C-4A4A-9D42-81ABACF1D6D4

P50

Q33911256-47DD80F6-D1FE-4150-A3A2-9D4721293250

Q33911256-AFF822B6-116A-4910-8719-CE7AE311F2FB

P577

Q33911256-40687FEA-9F43-4DC4-8F91-C41532D172EE

P698

Q33911256-96227AEF-CE06-44E1-9F54-F44BC2005EAC

P921

Q33911256-3D2B1A01-B7CA-4846-9D4B-978D09D210CA

P932

Q33911256-B4BF0943-6E89-4FFE-909D-27644C3393B5

P356

JIMMUNOL.1300683

P1433

Journal of Immunology

P1476

Requirement for MyD88 signalin ...... oduction in Lyn-deficient mice

@en

P2093

Andrew J Gross

http://www.w3.org/2001/XMLSchema#string

Anthony L DeFranco

http://www.w3.org/2001/XMLSchema#string

Chrystelle Lamagna

http://www.w3.org/2001/XMLSchema#string

Clifford A Lowell

http://www.w3.org/2001/XMLSchema#string

Haitao Shao

http://www.w3.org/2001/XMLSchema#string

Ming Ji

http://www.w3.org/2001/XMLSchema#string

Natalia Ramos-Hernández

http://www.w3.org/2001/XMLSchema#string

Patrizia Scapini

http://www.w3.org/2001/XMLSchema#string

P2860

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

Inhibition of the B cell by CD22: a requirement for Lyn

Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes

Lyn tyrosine kinase: accentuating the positive and the negative

SAP is required for generating long-term humoral immunity

Lupus-like kidney disease in mice deficient in the Src family tyrosine kinases Lyn and Fyn.

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance

Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.

P304

875-885

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.1300683

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

192

http://www.w3.org/2001/XMLSchema#string

P50

P577

2013-12-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

24379120

http://www.w3.org/2001/XMLSchema#string

P921

P932

4101002

http://www.w3.org/2001/XMLSchema#string