Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
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Interactions between CYP3A4 and Dietary PolyphenolsRole of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityInteractions among cytochromes P450 in microsomal membranes: oligomerization of cytochromes P450 3A4, 3A5, and 2E1 and its functional consequencesA large-scale allosteric transition in cytochrome P450 3A4 revealed by luminescence resonance energy transfer (LRET).Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsMechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomerConformational Mobility in Cytochrome P450 3A4 Explored by Pressure-Perturbation EPR SpectroscopyImmobilized Cytochrome P450 for Monitoring of P450-P450 Interactions and MetabolismThe use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4Physical Studies of P450-P450 Interactions: Predicting Quaternary Structures of P450 Complexes in Membranes from Their X-ray Crystal Structures.The functional effects of physical interactions involving cytochromes P450: putative mechanisms of action and the extent of these effects in biological membranes.Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes.Substrate Dependent Native Luminescence from Cytochromes P450 3A4, 2C9, and P450cam.Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.Two surfaces of cytochrome b5 with major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries.Inhibition of Human CYP3A4 by Rationally Designed Ritonavir-Like Compounds: Impact and Interplay of the Side Group Functionalities.High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4.Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function.Characterization of interactions among CYP1A2, CYP2B4, and NADPH-cytochrome P450 reductase: Identification of specific protein complexes.Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites.Drug-Drug Interactions between Atorvastatin and Dronedarone Mediated by Monomeric CYP3A4.Effects of polymorphic variation on the thermostability of heterogenous populations of CYP3A4 and CYP2C9 enzymes in solution
P2860
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P2860
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
@en
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
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type
label
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
@en
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
@nl
prefLabel
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
@en
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
@nl
P2860
P50
P356
P1433
P1476
Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.
@en
P2093
James R Halpert
Nadezhda Y Davydova
P2860
P304
P356
10.1042/BJ20130398
P407
P577
2013-07-01T00:00:00Z