Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.

about

Numerical analysis of time dependent inhibition kinetics: comparison between rat liver microsomes and rat hepatocyte data for mechanistic model fitting.Improved Predictions of Drug-Drug Interactions Mediated by Time-Dependent Inhibition of CYP3A.

P2860

Q36413309-84B37EEB-BD49-4C28-B09A-D5D98BD86B36 Q52334679-E9D77F00-90C4-4920-AFEF-9DA5BEC66A3A

P2860

Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.

Item

http://www.wikidata.org/entity/Q41432197

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Mechanism-Based Inhibition of ...... in Vitro/in Vivo Correlations.

@en

type

Item

label

Mechanism-Based Inhibition of ...... in Vitro/in Vivo Correlations.

@en

prefLabel

Mechanism-Based Inhibition of ...... in Vitro/in Vivo Correlations.

@en

P1476

Mechanism-Based Inhibition of ...... in Vitro/in Vivo Correlations.

@en

P2093

Jaydeep Yadav

http://www.w3.org/2001/XMLSchema#string

Jeffrey P Jones

http://www.w3.org/2001/XMLSchema#string

Ken Korzekwa

http://www.w3.org/2001/XMLSchema#string

Swati Nagar

http://www.w3.org/2001/XMLSchema#string

P2860

Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives

A numerical method for analysis of in vitro time-dependent inhibition data. Part 1. Theoretical considerations

Comparison of different algorithms for predicting clinical drug-drug interactions, based on the use of CYP3A4 in vitro data: predictions of compounds as precipitants of interaction.

Predicting clearance in humans from in vitro data.

Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions.

A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.

Human cytochrome p450 inhibition and metabolic-intermediate complex formation by goldenseal extract and its methylenedioxyphenyl components.

Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions.

Substrate binding to cytochromes P450.

Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone.

P304

2833-2843

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/ACS.MOLPHARMACEUT.6B00436

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Carlo Barnaba

P577

2016-06-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

27336918

http://www.w3.org/2001/XMLSchema#string

P932

5059843

http://www.w3.org/2001/XMLSchema#string

Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.

about

P2860

P2860

Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932