Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects. - Wikidata - wikimedia - TriplyDB

Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.

Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.

http://www.wikidata.org/entity/Q37512434

about

Tumor microenvironment and neurofibromatosis type I: connecting the GAPs In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies Eliminating barriers to personalized medicine: learning from neurofibromatosis type 1 An integrative view on sex differences in brain tumors Neurofibromatosis type 1 - a model for nervous system tumour formation?Optimizing biologically targeted clinical trials for neurofibromatosis.Sexually dimorphic RB inactivation underlies mesenchymal glioblastoma prevalence in males A framework for detecting and characterizing genetic background-dependent imprinting effects.Genetic modifiers of neurofibromatosis type 1-associated café-au-lait macule count identified using multi-platform analysis.An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.Harnessing preclinical mouse models to inform human clinical cancer trials.Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.Resistance to oncolytic myxoma virus therapy in nf1(-/-)/trp53(-/-) syngeneic mouse glioma models is independent of anti-viral type-I interferon.Increased survival following tumorigenesis in Ts65Dn mice that model Down syndrome.Control of proliferation in astrocytoma cells by the receptor tyrosine kinase/PI3K/AKT signaling axis and the use of PI-103 and TCN as potential anti-astrocytoma therapies.Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.Arlm1 is a male-specific modifier of astrocytoma resistance on mouse Chr 12.Scram1 is a modifier of spinal cord resistance for astrocytoma on mouse Chr 5.Modeling cognitive dysfunction in neurofibromatosis-1 Pediatric gliomas as neurodevelopmental disorders Real-time PCR analysis of candidate imprinted genes on mouse chromosome 11 shows balanced expression from the maternal and paternal chromosomes and strain-specific variation in expression levels.Parent-of-origin in individuals with familial neurofibromatosis type 1 and optic pathway gliomas.Using neurofibromatosis-1 to better understand and treat pediatric low-grade glioma Rethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop.De novo induction of genetically engineered brain tumors in mice using plasmid DNA Chr 19(A/J) modifies tumor resistance in a sex- and parent-of-origin-specific manner.Brain tumor susceptibility: the role of genetic factors and uses of mouse models to unravel risk.PTEN dosage is essential for neurofibroma development and malignant transformation Mouse chromosome 11 harbors genetic determinants of hippocampal strain-specific nicotinic receptor expression.Molecular epigenetics and genetics in neuro-oncology.EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors.Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.The ecology of brain tumors: lessons learned from neurofibromatosis-1.Genetic modeling of gliomas in mice: new tools to tackle old problems.Review: low-grade gliomas as neurodevelopmental disorders: insights from mouse models of neurofibromatosis-1.The molecular and cell biology of pediatric low-grade gliomas.Mouse models of glioblastoma: lessons learned and questions to be answered.Improving outcomes for neurofibromatosis 1-associated brain tumors.Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii.M011L-deficient oncolytic myxoma virus induces apoptosis in brain tumor-initiating cells and enhances survival in a novel immunocompetent mouse model of glioblastoma

P2860

Q24654681-25C1C20F-2BF3-4792-A01C-4289718CACC9 Q26820289-278D7524-0F5F-4D6C-8150-24F74B227826 Q26828988-24BC4988-7303-4BE5-9C03-C9BD8AA666B9 Q26829861-71E8DC96-DCED-4E25-93C8-285B0A244B94 Q28265284-CFCADF8E-A97B-4DB9-8752-0133D5820A1C Q30438898-31C2CA19-FFF0-4538-A6D3-B55D8447F222 Q34117529-BA1FB86A-FCF0-438A-B0DE-A4029A451000 Q34287133-D6C2773F-6AC8-474F-ABAD-60B1A38847F3 Q34350807-B36B297F-3611-431E-900F-647740FDA30C Q34448414-3EBF8B88-5E67-41B0-B39B-78B8AEE5DB2F Q34498952-AC1654FC-9DBD-42AC-A517-C392D0B3A0F1 Q34509145-C1490E65-9809-46F7-A7C5-F84F98FB2972 Q34770256-BED0B3AB-E031-4B85-90BD-3E905370AB84 Q34988075-68F6C514-3311-4ABA-B43A-2B1AA4DE827A Q35021348-20DBECBA-D2F4-41CB-AC8B-231EA35913C9 Q35639252-8C4D50DD-4F02-4EB2-976D-E68BB6D04546 Q35696405-BED59FA9-D8DB-4B02-BE12-100CD24AD526 Q35823362-A1683B65-2315-4EC5-967D-9C0D34BE741C Q36756183-2A5C6134-84C0-440D-9272-BD7BB0F5F86F Q36803476-615EBCD5-9A14-4F07-ABE1-564C706BC0B7 Q36828777-120F1CFB-4988-4DE8-824E-221FAA95319C Q36958006-E4E841D4-D87D-42D4-B000-B79C10DD1D72 Q36968955-6D0996B2-FB81-472A-9B40-2294779B1480 Q37182261-D31B34EC-8E64-4F44-9821-4F154F8896F3 Q37240292-7DA830ED-D959-40C9-949F-32771470AB13 Q37267802-861004C6-8D61-41B0-8B26-C679A731371E Q37348713-D944DD89-BF18-41ED-988A-67440B7DC656 Q37395587-337C7A24-522E-4223-9AB8-6267BE4C50C3 Q37417061-76EC37A1-59A0-40F7-AA61-2443ACB16C86 Q37533620-294741DF-1AA8-47DD-B2A7-2F154E0AA596 Q37582297-EF6A28D2-D49B-4E9A-9C96-84304A41A709 Q37729676-AC96C77F-BEB8-46B0-8521-7DF231F81785 Q37809458-3A392C16-83AF-418B-AA66-E2DD2854A857 Q37838362-B06003DD-DC95-4D94-9A8D-36DA15ED4C6C Q37950470-C1EA6567-8312-4AA5-9AE8-F2EFAE8D2DB9 Q38102568-BD311D04-7AEB-47FF-A08B-4B981E0C4A04 Q38187576-69A18B58-28BB-44B0-B396-5CE0F6F7AE31 Q38344456-56F7304C-C1A6-451B-95E6-153F780453DD Q38613674-823F0AB2-19D5-4C67-AE3C-57511BBC0517 Q39932965-0790B414-EFE8-484A-90A4-230B85271446

P2860

Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.

http://www.wikidata.org/entity/Q37512434

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 19 August 2004

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@en

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@nl

type

label

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@en

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@nl

prefLabel

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@en

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@nl

P1433

Q37512434-25FC326D-8474-43A0-A58A-9AE9C531E819

P1476

Q37512434-7CFD1605-B718-48D2-879B-02A53091A51D

P2093

Q37512434-0D135D9B-885D-4B9B-A6F1-49DA0017C764

Q37512434-1ADEA038-BEBC-4AF0-A71D-10CC5DAEC197

Q37512434-44CE54B3-A385-4D28-B0E6-0ED1A46ECA45

Q37512434-56332E4B-A1B2-465D-BB60-4878874772AC

Q37512434-690F255F-11FE-4525-87FC-2BC55F14D6D7

Q37512434-92D91B12-F110-4D69-8A93-C9A446D9C75E

Q37512434-9ED136C1-F12B-4E87-AE5A-03101E28FAF5

Q37512434-BAF443C1-1CD6-48EF-A420-2F47B3971BD1

Q37512434-BBE93A5A-C53A-41E9-8A22-8BE27E61105E

Q37512434-FB1DFF38-8BE0-433C-A1E8-AEDB51414170

P2860

Q37512434-0CA20A5E-A905-4AFC-980A-D53627A62B1C

Q37512434-165A6864-8FA9-491C-9FB0-B0723F7AD5AD

Q37512434-1667AB64-CA17-4DE4-BE08-4167B716E486

Q37512434-1826A169-E536-4B0A-9041-9DC1F854F693

Q37512434-1ED4C4AB-B26D-47B2-A95B-4ACC34C7A1DA

Q37512434-31831503-0AE4-4A6A-A9F7-9DA727988BBE

Q37512434-3789ED00-B9BE-48C3-AA16-5AACD7A838B4

Q37512434-4FA7341E-BD2D-4404-9A6D-ABE1AE4E988D

Q37512434-53FC7926-39A2-4623-8D68-6D9D77C91EA7

Q37512434-571B02A7-356D-4B5E-8FC5-DF5B3D1D28A2

P304

Q37512434-9EAAC875-9ABF-4E7C-A786-47DCEF762639

P31

Q37512434-4C434E7C-398D-474D-B0B3-865DA2C34893

P356

Q37512434-7094C027-042C-4886-AB20-E564B38ABB67

P407

Q37512434-60D05DD2-16A7-4C1B-8F26-BDCB062AC9C9

P433

Q37512434-B53D6411-C0E0-43EA-83CC-95582EC6CCA5

P478

Q37512434-5DCA13B5-DD5A-4FD3-B50F-E621185DD260

P577

Q37512434-C22CE951-1B6A-47F2-A629-EAB60718F89B

P5875

Q37512434-A7164EA3-43C3-4006-8410-B55886F5AFD2

P698

Q37512434-5C9AE784-9A48-4D04-B735-C917F8A732C5

P932

Q37512434-74B2A0B1-33E9-43E6-9A79-6E1EE6D7DB1A

P356

PNAS.0401236101

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Susceptibility to astrocytoma ...... subject to epigenetic effects.

@en

P2093

C Dahlem Smith

http://www.w3.org/2001/XMLSchema#string

Dagan A Loisel

http://www.w3.org/2001/XMLSchema#string

David J Munroe

http://www.w3.org/2001/XMLSchema#string

Emily Christy

http://www.w3.org/2001/XMLSchema#string

Jeremy Ledger

http://www.w3.org/2001/XMLSchema#string

Karlyne M Reilly

http://www.w3.org/2001/XMLSchema#string

Robert G Tuskan

http://www.w3.org/2001/XMLSchema#string

Roderick T Bronson

http://www.w3.org/2001/XMLSchema#string

Shirley Tsang

http://www.w3.org/2001/XMLSchema#string

Tyler Jacks

http://www.w3.org/2001/XMLSchema#string

P2860

RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.

Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects

Mouse models of tumor development in neurofibromatosis type 1

Mouse tumor model for neurofibromatosis type 1

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

Tumor spectrum analysis in p53-mutant mice

SPARC: a signal of astrocytic neoplastic transformation and reactive response in human primary and xenograft gliomas.

A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice.

p53 mutations are associated with 17p allelic loss in grade II and grade III astrocytoma.

Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum.

P304

13008-13013

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0401236101

http://www.w3.org/2001/XMLSchema#string

P407

P433

35

http://www.w3.org/2001/XMLSchema#string

P478

101

http://www.w3.org/2001/XMLSchema#string

P577

2004-08-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8393075

http://www.w3.org/2001/XMLSchema#string

P698

15319471

http://www.w3.org/2001/XMLSchema#string

P932

516509

http://www.w3.org/2001/XMLSchema#string