A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice.
about
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancerTumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiersSequential and morphological analyses of aberrant crypt foci formation in mice of differing susceptibility to azoxymethane-induced colon carcinogenesisMlh1 deficiency enhances several phenotypes of Apc(Min)/+ miceImportance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesisRegulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signalingDistinguishing between cancer driver and passenger gene alteration candidates via cross-species comparison: a pilot study.Stem cells: the intestinal stem cell as a paradigm.Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesisReduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic mice.Clusterin as a biomarker in murine and human intestinal neoplasiaMonoallelic silencing and haploinsufficiency in early murine intestinal neoplasms.The modifier of Min 2 (Mom2) locus: embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression.Genetic Manipulation of Homologous Recombination In Vivo Attenuates Intestinal Tumorigenesis.Identification of Mom7, a novel modifier of Apc(Min/+) on mouse chromosome 18.Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function.Enhanced intestinal tumor multiplicity and grade in vivo after HZE exposure: mouse models for space radiation risk estimatesHelicobacter hepaticus infection promotes colon tumorigenesis in the BALB/c-Rag2(-/-) Apc(Min/+) mouse.More than two decades of Apc modeling in rodentsThe pleiotropic phenotype of Apc mutations in the mouse: allele specificity and effects of the genetic background.Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis.Transgenic mice carrying the H258N mutation in the gene encoding the beta-subunit of phosphodiesterase-6 (PDE6B) provide a model for human congenital stationary night blindness.Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway.Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.APC and its modifiers in colon cancer.Functional allelic loss detected at the protein level in archival human tumours using allele-specific E-cadherin monoclonal antibodies.Loss of HLTF function promotes intestinal carcinogenesis.A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity.Two-hit model for progression of medulloblastoma preneoplasia in Patched heterozygous mice.
P2860
Q24685630-BED19907-6754-49A2-88F0-EE8B619FCC18Q28507960-815523C5-BF05-4B77-BDEC-B5B51C42CC35Q28510209-9EF45772-A979-435D-96E8-B421168EE40FQ28588324-BEF67837-B6B5-482C-A224-ACC0C8CAD856Q28593435-53FCB0E1-D0BA-495A-986C-68D8DE9C58DCQ33334385-3E999A51-C411-4271-8A16-298787926EA1Q33657370-9D65DE96-B9AF-4E1D-9B52-25A6FE9F85B6Q33846215-6385496A-8987-4E31-8A8C-A45875758A8AQ34016094-9D87AA02-4E8A-4953-BE8D-32CB6566EFACQ35020444-5435B9C1-0CB8-4A1F-A179-CCDB9112B3EAQ35234858-10E803AC-397B-45DF-A7BB-B8633E9CD4CAQ35750900-CA177DA2-5C17-4778-8836-3DD2CE6FAAC1Q35757899-30D1ABB5-B5B0-40E5-A02B-4ECE47A616B1Q35815688-2FEB7BD8-8AA7-4944-AC18-41B90F537820Q35846272-DD6363E8-E586-422F-A155-A076316209CAQ36448895-538D1FF5-32A5-4F04-BB6A-13EA4367F863Q36632251-E9B7ECA4-3DFA-432B-96BA-8379F956D415Q36710676-8BFF2823-47BF-43DD-9189-7ADBBDBD6A82Q36847248-70330C5B-2796-4DA7-8F65-852505C28860Q36873796-B861E970-5382-42E2-85B8-496CCE78EE1BQ36899713-1328EF8B-3EE2-464F-B831-CDF26B1BA618Q37365664-6D1200EB-DEAB-4EFC-A94A-3A1387EC09DAQ37416970-51B42BFC-544F-490F-AFB3-1BD0A20E8513Q37512434-1826A169-E536-4B0A-9041-9DC1F854F693Q37635945-7101FD51-18D8-454A-A2A6-EF5A1C9E070FQ38455319-2C32F172-1428-4B72-99B0-7A7EDAC1EDFDQ42136714-B2493059-D585-4099-9FCE-26D68C1D2F1BQ52548391-065BF238-F9F9-4AF4-82E6-A0C74D8F80B2Q55470193-2C5E0F08-9150-44B4-AE4B-7CC52475288A
P2860
A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice.
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@ast
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@en
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@nl
type
label
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@ast
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@en
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@nl
prefLabel
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@ast
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@en
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@nl
P2093
P2860
P356
P1476
A resistant genetic background ...... terozygosity in ApcMin/+ mice.
@en
P2093
A R Shoemaker
C A Midgley
M A Newton
P2860
P304
10826-10831
P356
10.1073/PNAS.95.18.10826
P407
P577
1998-09-01T00:00:00Z