Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals
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G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeNascent RNA transcripts facilitate the formation of G-quadruplexes.A competitive formation of DNA:RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming sitePotential non-B DNA regions in the human genome are associated with higher rates of nucleotide mutation and expression variation.A parallel quadruplex DNA is bound tightly but unfolded slowly by pif1 helicase.DECKO: Single-oligo, dual-CRISPR deletion of genomic elements including long non-coding RNAsGuanine-vacancy-bearing G-quadruplexes responsive to guanine derivatives.Yeast Helicase Pif1 Unwinds RNA:DNA Hybrids with Higher Processivity than DNA:DNA Duplexes.Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands.RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms.Strand-Biased Formation of G-Quadruplexes in DNA Duplexes Transcribed with T7 RNA Polymerase.Structural switch from a multistranded G-quadruplex to single strands as a consequence of point mutation in the promoter of the human GRIN1 gene.RNA G-Quadruplexes as Key Motifs of the Transcriptome.Formation of DNA:RNA hybrid G-quadruplexes of two G-quartet layers in transcription: expansion of the prevalence and diversity of G-quadruplexes in genomes.Formation of DNA:RNA hybrid G-quadruplex in bacterial cells and its dominance over the intramolecular DNA G-quadruplex in mediating transcription termination.
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P2860
Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Bioinformatic analysis reveals ...... ements in warm-blooded animals
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Bioinformatic analysis reveals ...... ments in warm-blooded animals.
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Bioinformatic analysis reveals ...... ements in warm-blooded animals
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Bioinformatic analysis reveals ...... ments in warm-blooded animals.
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Bioinformatic analysis reveals ...... ements in warm-blooded animals
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Bioinformatic analysis reveals ...... ments in warm-blooded animals.
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Bioinformatic analysis reveals ...... ements in warm-blooded animals
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Jia-Yu Zhang
Ke-Wei Zheng
Yu-Hua Hao
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10379-10390
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10.1093/NAR/GKT781
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P577
2013-09-02T00:00:00Z