Alloreactive T cells discriminate among a diverse set of endogenous peptides.
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Use of recombinant protein to identify a motif-negative human cytotoxic T-cell epitope presented by HLA-A2 in the hepatitis C virus NS3 regionA Naturally Selected Dimorphism within the HLA-B44 Supertype Alters Class I Structure, Peptide Repertoire, and T Cell RecognitionStructural Basis for T Cell Alloreactivity among Three HLA-B14 and HLA-B27 AntigensWhat Is Direct Allorecognition?Pillars article: Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry. Science 1992. 255: 1261-1263.Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells.Definition of agonists and design of antagonists for alloreactive T cell clones using synthetic peptide libraries.Two HLA-B14 subtypes (B*1402 and B*1403) differentially associated with ankylosing spondylitis differ substantially in peptide specificity but have limited peptide and T-cell epitope sharing with HLA-B27.The peptide p2Ca is immunodominant in allorecognition of Ld by beta chain variable region V beta 8+ but not V beta 8- strains.Alloreactive cytotoxic T lymphocytes recognize epitopes determined by both the alpha helices and beta sheets of the class I peptide binding site.Anchoring pockets in human histocompatibility complex leukocyte antigen (HLA) class I molecules: analysis of the conserved B ("45") pocket of HLA-B27Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity.TL antigen as a transplantation antigen recognized by TL-restricted cytotoxic T cellsRecognition of multiple peptide cores by a single T cell receptor.A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells.Peptide-independent recognition by alloreactive cytotoxic T lymphocytes (CTL).A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations.Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptidesA ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell cloneSingle-residue changes in class I major histocompatibility complex molecules stimulate responses to self peptidesMHC restriction and allogeneic immune responses.Endogenous-peptide-dependent alloreactivity: new scientific insights and clinical implications.Effect of crossmatching on outcome in organ transplantation.CD8+ T cell tolerance and autoimmunity to extra-thymic antigens.Peptide dependency of alloreactive CD4+ T cell responses.T cell receptor (TCR) repertoire in alloimmune responses.The contribution of peptides to T cell allorecognition and allograft rejection.In vivo expansion of HLA-B35 alloreactive T cells sharing homologous T cell receptors: evidence for maintenance of an oligoclonally dominated allospecificity by persistent stimulation with an autologous MHC/peptide complexHigh-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade.Mechanisms of Tolerance Induction by Hematopoietic Chimerism: The Immune Perspective.Alloreactive T cells respond specifically to multiple distinct peptide-MHC complexes.Differential ability of isolated H-2 Kb subsets to serve as TCR ligands for allo-specific CTL clones: potential role for N-linked glycosylation.A similarity in peptide cross-reactivity between alloantigen- and nominal antigen-induced CD8+ T cell responses in vitro.Alloreactivity between disparate cognate and allogeneic pMHC-I complexes is the result of highly focused, peptide-dependent structural mimicry.Identification of the novel allele HLA-B*1546 which belongs to the serological B72 type: implications for bone marrow transplantation.
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Alloreactive T cells discriminate among a diverse set of endogenous peptides.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@en
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@nl
type
label
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@en
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@nl
prefLabel
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@en
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@nl
P2093
P2860
P356
P1476
Alloreactive T cells discriminate among a diverse set of endogenous peptides.
@en
P2093
L A Sherman
M F Mescher
P2860
P304
P356
10.1073/PNAS.88.12.5101
P407
P577
1991-06-01T00:00:00Z