Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?
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Cross-Reactivity of TCR Repertoire: Current Concepts, Challenges, and Implication for AllotransplantationCrystal structure of a T cell receptor bound to an allogeneic MHC moleculeStructural Comparison of Allogeneic and Syngeneic T Cell Receptor–Peptide-Major Histocompatibility Complex ComplexesStructural Basis for T Cell Alloreactivity among Three HLA-B14 and HLA-B27 AntigensStructural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restrictionStructural evidence of T cell xeno-reactivity in the absence of molecular mimicryWhat Is Direct Allorecognition?Clonal sketches of the immune responseAntigenicity and immunogenicity of allogeneic retinal transplantsThe Tritope Model for restrictive recognition of antigen by T-cells II. Implications for ontogeny, evolution and physiologyDirect identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells.The peptide-specific alloreactive human T cell repertoire varies largely between individuals and is not extended in HLA-A*0205--anti-HLA-A*0201 pairings.Alloreactivity: an old puzzle revisited.The standard model of T-cell receptor function: a critical reassessment.Peptide-mediated modulation of T-cell allorecognition.Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule.Recognition of xeno-(HLA, SLA) major histocompatibility complex antigens by mouse cytotoxic T cells is not H-2 restricted: a study with transgenic mice.Allorecognition of DR1 by T cells from a DR4/DRw13 responder mimics self-restricted recognition of endogenous peptides.Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.Restricted and conserved T-cell repertoires involved in allorecognition of class II major histocompatibility complex.An in depth analysis of the concept of "polyspecificity" assumed to characterize TCR/BCR recognitionLessons from cardiac transplantation in infancyDoes OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?Inhibition of allorecognition by an H-2Kb-derived peptide is evidence for a T-cell binding region on a major histocompatibility complex molecule.Alloreactivity studied with mutants of HLA-A2.Self peptides and the peptidic self.Uncertainties - discrepancies in immunology.On the logic of restrictive recognition of peptide by the T-cell antigen receptor.Alloreactivity across HLA barriers is mediated by both naïve and antigen-experienced T cells.Anti-CD4 monoclonal antibodies in therapy: creation of nonclassical tolerance in the adult.Evolutionarily conserved features contribute to αβ T cell receptor specificityPeripheral blood leukocyte grafts that induce human to mouse graft-vs.-host disease reject allogeneic human skin grafts.Mixed chimerism and split tolerance: mechanisms and clinical correlations.The peptide p2Ca is immunodominant in allorecognition of Ld by beta chain variable region V beta 8+ but not V beta 8- strains.High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.The major histocompatibility complex in transplantationNegative selection imparts peptide specificity to the mature T cell repertoire.Human mature T cells that are anergic in vivo prevail in SCID mice reconstituted with human peripheral blood.Alloreactive cytotoxic T lymphocytes recognize epitopes determined by both the alpha helices and beta sheets of the class I peptide binding site.The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice
P2860
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P2860
Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
1977年论文
@zh
1977年论文
@zh-cn
name
Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?
@en
type
label
Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?
@en
prefLabel
Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?
@en
P1433
P1476
Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens?
@en
P2093
P356
10.1016/0008-8749(77)90269-6
P577
1977-03-01T00:00:00Z