Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs. - Wikidata - wikimedia - TriplyDB

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs.

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs.

http://www.wikidata.org/entity/Q37536687

about

Structural studies of CNG repeats The panorama of miRNA-mediated mechanisms in mammalian cells Targeting several CAG expansion diseases by a single antisense oligonucleotide Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models Oligonucleotide-based strategies to combat polyglutamine diseases.Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs.Allele-specific silencing of mutant Ataxin-7 in SCA7 patient-derived fibroblasts.Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target Toward understanding Machado-Joseph disease Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.Allele-selective inhibition of trinucleotide repeat genes.Mechanism of allele-selective inhibition of huntingtin expression by duplex RNAs that target CAG repeats: function through the RNAi pathway Recent advances in RNA interference therapeutics for CNS diseases.RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression.Toward RNAi therapy for the polyglutamine disease Machado-Joseph disease ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy.Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions.Mutant CAG Repeats Effectively Targeted by RNA Interference in SCA7 Cells.Consensus paper: pathological mechanisms underlying neurodegeneration in spinocerebellar ataxias.Oligonucleotides for upregulating gene expression.Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.Self-duplexing CUG repeats selectively inhibit mutant huntingtin expression miR-25 alleviates polyQ-mediated cytotoxicity by silencing ATXN3.

P2860

Q26851232-9738F402-63B4-4BF7-ADF2-21FE84156AEC Q27001268-80E35AB4-B272-4FA6-B7B4-AB485B6FF7C8 Q28740870-28609DAB-D22C-4233-A3F3-B251874C7975 Q33635375-A79220F2-428F-4FC9-863B-BBD649AD1F6C Q33791247-9DFFB8BD-259F-45DE-833E-0B43D06504F2 Q33939348-33FD8B49-7F24-4F08-BE86-71BA8F646534 Q34508264-9F5DC114-5E07-4D39-9F36-6F269D6E846B Q35633648-B6540129-3285-4BC5-A4FA-C5E4DC9FE764 Q35837355-04A6C756-2114-4708-80A9-FBC504807032 Q36239309-70589F57-7CDB-43DF-B2D1-4FAD86B2AA55 Q36310758-B33E8A31-2164-457B-86CE-1F3D0EE4243A Q36477988-786CEDE5-0967-4DBE-A108-A472C1FA5F48 Q36983193-A4CAB3A0-4CB9-4EC4-A6B6-60E03DA7D408 Q37224701-D87462D5-79D6-4576-A991-EDBA3F6E2BC4 Q37254846-DBBACF31-2619-483A-BBC5-9A3ADEC41A0A Q37271206-33CDA984-09DD-447E-9A23-82E311687A1F Q37483574-7A243A7A-581C-457A-B6C5-0EE90855A730 Q37539531-0B00892C-30AE-42BB-A6D0-9DDE2968D7B1 Q37619548-00C8BD36-F7DF-46F6-8BEC-955C873E6572 Q38162970-6B681136-400A-4B0F-8232-5B39BBCD409A Q38167681-102F96A1-534F-4ECB-8A66-39ED54D59233 Q41898404-E054A998-BAE0-4944-AB1A-CAAEC7414C19 Q50609525-EC1371FD-A5E1-49F6-9F98-5C61471C4D3B

P2860

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs.

http://www.wikidata.org/entity/Q37536687

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 07 February 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Allele-selective inhibition of ...... nse oligomers and duplex RNAs.

@en

Allele-selective inhibition of ataxin-3

@nl

type

label

Allele-selective inhibition of ...... nse oligomers and duplex RNAs.

@en

Allele-selective inhibition of ataxin-3

@nl

prefLabel

Allele-selective inhibition of ...... nse oligomers and duplex RNAs.

@en

Allele-selective inhibition of ataxin-3

@nl

P1433

Q37536687-534E044F-2763-48C8-AEE5-846719DDFA81

P1476

Q37536687-AB561E40-1D76-4CE7-8F56-66F9DBE6A504

P2093

Q37536687-0D57FBE3-8BEC-457F-B9AD-EE91CFAF099B

Q37536687-615E5CBF-E25C-4776-BAA6-AED14BFAA284

Q37536687-61DF9B35-A8C0-4003-BD3B-DCD81BE05B84

Q37536687-733F33EC-B5A8-46CF-824A-FCDF077FF33C

Q37536687-95ED7AAA-D293-4B69-AA54-E378640E3011

Q37536687-A29A8C37-20B6-4C4A-89D2-5A405379E134

Q37536687-A399344B-F09E-4B2A-9C88-A1D9732A3A85

Q37536687-E59C2872-9E2E-41A8-B652-87BA7DA9B7A7

Q37536687-EC93E5C7-9EC7-45DE-8396-77BF8E8C3688

P2860

Q37536687-14523512-1D11-4557-A4A1-80C129AC73D2

Q37536687-1A9E4F41-8E04-46FF-BC3D-6D76C8560CB9

Q37536687-1AAF92E2-5AEF-45E2-8AE2-6478F4FDF021

Q37536687-2881148A-7C7D-44A1-AE6E-6C97BACAAC61

Q37536687-2E1E60C6-73B2-4290-8CE6-ED9C99A76F61

Q37536687-2F49873B-71A6-4A1D-A7E8-2B58C05228C1

Q37536687-33C76501-DE98-4BC8-A5CD-C7C0883C47C3

Q37536687-340A8C21-A57A-41D6-AFF6-38AF417F54D5

Q37536687-356E3F20-58B9-4A04-A61E-E192DF01DEBE

Q37536687-3CBAF167-931B-411B-8681-51B617FF4392

P304

Q37536687-F563D11C-C83D-415C-A1E9-1352D3AAA0CA

P31

Q37536687-789C6916-B9F7-4497-BD77-DAD5CC93E63C

P356

Q37536687-3F38A586-2F11-4725-ACEE-CF4D850467B8

P433

Q37536687-30E43D1A-F829-4403-88FD-A1E05879BB3E

P478

Q37536687-C0F5664B-C4DB-40CF-94D5-344AD2356955

P50

Q37536687-B9E8A5FC-30BD-4856-A26C-5AE8BAB535DF

P577

Q37536687-6BE8F9FB-56DA-4B61-94E3-97A2EA27428D

P5875

Q37536687-B3934E88-6FF6-4D3B-8712-D0E98798767B

P698

Q37536687-686DC0FD-83E6-462F-9BFF-D433E47F26DA

P932

Q37536687-6F21B35A-B882-40C6-8295-EDAC803CE09D

P356

P1433

Biological Chemistry

P1476

Allele-selective inhibition of ...... nse oligomers and duplex RNAs.

@en

P2093

C Frank Bennett

http://www.w3.org/2001/XMLSchema#string

David R Corey

http://www.w3.org/2001/XMLSchema#string

Eric E Swayze

http://www.w3.org/2001/XMLSchema#string

Jeja Syeda-Nawaz

http://www.w3.org/2001/XMLSchema#string

Jiaxin Hu

http://www.w3.org/2001/XMLSchema#string

Jing Liu

http://www.w3.org/2001/XMLSchema#string

John Randolph

http://www.w3.org/2001/XMLSchema#string

Jonathan K Watts

http://www.w3.org/2001/XMLSchema#string

Keith T Gagnon

http://www.w3.org/2001/XMLSchema#string

P2860

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases

Argonaute2 is the catalytic engine of mammalian RNAi

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

Trinucleotide Repeat Disorders

Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease.

Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.

Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design

P304

315-325

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1515/BC.2011.045

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

392

http://www.w3.org/2001/XMLSchema#string

P50

Jyoti Chattopadhyaya

P577

2011-02-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

228728995

http://www.w3.org/2001/XMLSchema#string

P698

21294677

http://www.w3.org/2001/XMLSchema#string

P932

3908450

http://www.w3.org/2001/XMLSchema#string