Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging.
about
Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.Interleukin-7 and Immunosenescence.Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells.Naive T cell maintenance and function in human aging.Innate and virtual memory T cells in man.Memory CD8+ T Cells: Orchestrators and Key Players of Innate Immunity?CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.Reduced naïve CD8(+) T-cell priming efficacy in elderly adults.Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged mice.Characterization of age-associated exhausted CD8⁺ T cells defined by increased expression of Tim-3 and PD-1.Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent mannerNADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs.Old Mice Accumulate Activated Effector CD4 T Cells Refractory to Regulatory T Cell-Induced Immunosuppression.Phenotype of NK-Like CD8(+) T Cells with Innate Features in Humans and Their Relevance in Cancer Diseases.Innate memory T cells.Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection.CD4+ virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity.Successful and Maladaptive T Cell Aging.Attrition of memory CD8 T cells during sepsis requires LFA-1Role of cell-intrinsic and environmental age-related changes in altered maintenance of murine T cells in lymphoid organs.The twilight of immunity: emerging concepts in aging of the immune system.Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow.Virtual memory cells make a major contribution to the response of aged influenza-naïve mice to influenza virus infection
P2860
Q30394063-AAAE6978-5F83-4278-B52E-467CADAA1BACQ33582101-BF008FD0-3B4A-47FC-B638-678078414E07Q34147526-B26286CC-9CFA-4C47-BC37-E854B99DD8DEQ35608970-4B85DACE-D1B7-4417-AF72-F362AB4F91B3Q35674471-6A996B42-DE7C-4F7E-BEC7-C2337A881642Q35966890-62F18A75-64B1-4796-B29C-CDF1C8E5AADFQ36120067-61D2FF0D-4EE2-448A-9B5C-0D5F4190F863Q36281282-E697690A-0E28-450E-BF5E-480DD5D174F1Q36475259-1B523953-88AC-41A4-805E-BB6E851C8B34Q36563266-D8FDB70D-3CD1-4A76-B247-136EAA70FD29Q36665452-09AB956A-85EA-411F-B310-F7931B677CB2Q36834641-DAC562A8-9E90-4C39-A415-7FE45D61E958Q36867379-719D0CF8-51D0-4D5A-9896-7F52D7C25A0FQ37714509-ECDB5543-6C91-4973-B98B-0E011802347BQ37721209-25063CBB-438A-4588-81B7-8D7F74DCDADCQ38366356-EE200807-8BD9-467E-AB72-73FDD140E2A4Q39023427-F38F7CD9-06B1-4F0F-8119-E71FDEE407BFQ39147742-246FBEDB-A5AD-48E1-95D0-13FAA371A227Q39193878-E7FB5F2C-3C0F-45D9-92F2-B98D062FA1D6Q39693010-78843966-5284-4EA1-8985-135CB1A6CE81Q40172582-82BEE930-FB1D-4235-98C8-BFABA6CB9B27Q47291933-C9485CB5-8917-41F5-A0B0-93EFCACD0B10Q50535196-F018B971-2F8F-44CA-A827-74EC2E2BAC2DQ58796345-7FB2500F-BD36-47D7-954C-78E033981A7E
P2860
Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Two separate defects affecting ...... e T cell responses with aging.
@en
Two separate defects affecting ...... e T cell responses with aging.
@nl
type
label
Two separate defects affecting ...... e T cell responses with aging.
@en
Two separate defects affecting ...... e T cell responses with aging.
@nl
prefLabel
Two separate defects affecting ...... e T cell responses with aging.
@en
Two separate defects affecting ...... e T cell responses with aging.
@nl
P2093
P2860
P356
P1476
Two separate defects affecting ...... e T cell responses with aging.
@en
P2093
Kristin R Renkema
Megan J Smithey
P2860
P304
P356
10.4049/JIMMUNOL.1301453
P407
P577
2013-11-29T00:00:00Z