Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy
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Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinomaCytochrome P-450 2C9 sensitizes human prostate tumor cells to cyclophosphamide via a bystander effectTargeting tumor suppressor networks for cancer therapeutics.Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice.HSVtk/GCV system on hepatoma carcinoma cells: Construction of the plasmid pcDNA3.1‑pAFP-TK and targeted killing effectAdenoviral-mediated gene transfer in wound healing.Improving the safety of cell therapy products by suicide gene transferGene therapy for malignant liver disease.Hypoxia-inducible regulation of a prodrug-activating enzyme for tumor-specific gene therapy.Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo.Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.Construction of an oncolytic herpes simplex virus that precisely targets hepatocellular carcinoma cells.Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.Breast cancer selective gene expression and therapy mediated by recombinant adenoviruses containing the DF3/MUC1 promoterTranscriptional targeting of herpes simplex virus for cell-specific replication.TK gene combined with mIL-2 and mGM-CSF genes in treatment of gastric cancerAdenoviral vectors: development and application.Gene-directed enzyme prodrug therapy: a review of enzyme/prodrug combinations.A novel HBV antisense RNA gene delivery system targeting hepatocellular carcinoma.Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenovirusesA truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice.Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosineTumour-specific arginine vasopressin promoter activation in small-cell lung cancer.Construction of retroviral vector carrying HSV-tk gene under control of human AFP enhancer core sequence and human pgk promotor.The transcriptional control region of the human carcinoembryonic antigen gene: DNA sequence and homology studies.Construction of retroviral vectors to induce a strong expression of human class interferon gene in human hepatocellular carcinoma cells in vitro.Genes, dreams, and cancer.Safeguarding clinical translation of pluripotent stem cells with suicide genes.Selective transgene expression for detection and elimination of contaminating carcinoma cells in hematopoietic stem cell sources.Using predrugs to optimize drug candidates.Accelerating immune reconstitution after hematopoietic stem cell transplantation.MIA (melanoma inhibitory activity) promoter mediated tissue-specific suicide gene therapy of malignant melanoma.Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase.Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues.In vivo retrovirus-mediated herpes simplex virus thymidine kinase gene therapy approach for adult T cell leukemia in a rat model.Regulated expression of artificial chimeric genes contained in retroviral vectors: implications for virus-directed enzyme prodrug therapy (VDEPT) and other gene therapy applications.Development of drug targeting based on recombinant expression of the chicken avidin gene.Gene therapy for cancers.Gene therapy in gastroenterology.Interaction of the recombinant herpes simplex virus type 1 thymidine kinase with thymidine and aciclovir: a kinetic study.
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P2860
Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Retroviral-mediated gene thera ...... ve approach for cancer therapy
@en
Retroviral-mediated gene thera ...... e approach for cancer therapy.
@nl
type
label
Retroviral-mediated gene thera ...... ve approach for cancer therapy
@en
Retroviral-mediated gene thera ...... e approach for cancer therapy.
@nl
prefLabel
Retroviral-mediated gene thera ...... ve approach for cancer therapy
@en
Retroviral-mediated gene thera ...... e approach for cancer therapy.
@nl
P2093
P2860
P356
P1476
Retroviral-mediated gene thera ...... ve approach for cancer therapy
@en
P2093
Krenitsky TA
Richards CA
P2860
P304
P356
10.1073/PNAS.88.18.8039
P407
P577
1991-09-01T00:00:00Z