Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer. - Wikidata - wikimedia - TriplyDB

Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer.

Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer.

http://www.wikidata.org/entity/Q37593559

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Novel drugs that target the metabolic reprogramming in renal cell cancer Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis Lactate Contribution to the Tumor Microenvironment: Mechanisms, Effects on Immune Cells and Therapeutic Relevance Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis SLC transporters as therapeutic targets: emerging opportunities Reexamining cancer metabolism: Lactate production for carcinogenesis could be the purpose and explanation of the Warburg effect Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symporters Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors Attacking the supply wagons to starve cancer cells to death.Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.Optimisation of immunofluorescence methods to determine MCT1 and MCT4 expression in circulating tumour cells AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts.Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation.Mitochondrial Metabolism as a Treatment Target in Anaplastic Thyroid Cancer.Recent Advances in Targeting Tumor Energy Metabolism with Tumor Acidosis as a Biomarker of Drug Efficacy.MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4 Molecular Targets for Small-Molecule Modulators of Circadian Clocks.Vasculogenic mimicry in small cell lung cancer.MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate.Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium.Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.Cancer metabolism: targeting cancer universality.Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors.Hypoxia and cellular metabolism in tumour pathophysiology.Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma.Monocarboxylate transporter 1 contributes to growth factor-induced tumor cell migration independent of transporter activity.Monocarboxylate Transporters: Therapeutic Targets and Prognostic Factors in Disease.Trimming the Vascular Tree in Tumors: Metabolic and Immune Adaptations.Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity.Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State.MCT1 Inhibitor AZD3965 Increases Mitochondrial Metabolism, Facilitating Combination Therapy and Noninvasive Magnetic Resonance Spectroscopy.Lactate stimulates CA IX expression in normoxic cancer cells.Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.Tumour acidosis: from the passenger to the driver's seat.Novel carbonic anhydrase IX-targeted therapy enhances the anti-tumour effects of cisplatin in small cell lung cancer.

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P2860

Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer.

http://www.wikidata.org/entity/Q37593559

description

2013 nî lūn-bûn

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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2013年學術文章

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name

Activity of the monocarboxylat ...... 965 in small cell lung cancer.

@en

Activity of the monocarboxylat ...... 965 in small cell lung cancer.

@nl

type

label

Activity of the monocarboxylat ...... 965 in small cell lung cancer.

@en

Activity of the monocarboxylat ...... 965 in small cell lung cancer.

@nl

prefLabel

Activity of the monocarboxylat ...... 965 in small cell lung cancer.

@en

Activity of the monocarboxylat ...... 965 in small cell lung cancer.

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Clinical Cancer Research

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Activity of the monocarboxylat ...... 965 in small cell lung cancer.

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Alberto Fusi

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Cassandra L Hodgkinson

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Christopher J Morrow

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Daisuke Nonaka

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Francesca Trapani

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Paul W Bishop

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Radosław Polański

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P2860

Hallmarks of Cancer: The Next Generation

Platinum versus non-platinum chemotherapy regimens for small cell lung cancer

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

A small-cell lung cancer genome with complex signatures of tobacco exposure

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.

Targeting HIF-1 for cancer therapy

Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients

Regulation of cancer cell metabolism

A versatile viral system for expression and depletion of proteins in mammalian cells

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926-937

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3929348

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