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A role for proteinase-activated receptor-1 in inflammatory bowel diseases

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

http://www.wikidata.org/entity/Q37602792

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Main ion channels and receptors associated with visceral hypersensitivity in irritable bowel syndrome Endothelial dysfunction in cirrhosis: Role of inflammation and oxidative stress Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications Thrombin receptors and their antagonists: an update on the patent literature Functional GI disorders: from animal models to drug development.Regulatory network of inflammation downstream of proteinase-activated receptors Mandatory role of proteinase-activated receptor 1 in experimental bladder inflammation Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation.Functional role of kallikrein 6 in regulating immune cell survival.Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo Haemostatic system in inflammatory bowel diseases: new players in gut inflammation.Insulin-like growth factor-1 receptor transactivation modulates the inflammatory and proliferative responses of neurotensin in human colonic epithelial cells.Protease-activated receptor (PAR)2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.Transgenic mice rich in endogenous omega-3 fatty acids are protected from colitis Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents.Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells.Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2.Clinical relevance of proteinase activated receptors (pars) in the gut Tissue factor: a mediator of inflammatory cell recruitment, tissue injury, and thrombus formation in experimental colitis.Inhibition of protease-activated receptor 1 ameliorates intestinal radiation mucositis in a preclinical rat model.Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury Activated protein C-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin Anti-Inflammatory mechanisms of enteric Heligmosomoides polygyrus infection against trinitrobenzene sulfonic acid-induced colitis in a murine model.The mast cell integrates the splanchnic and systemic inflammatory response in portal hypertension.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.The protein C pathway and pathologic processes Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways Targeting PAR1: Now What?The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation.Expression and Clinical Significance of Elafin in Inflammatory Bowel Disease.Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine.Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1.

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P2860

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

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2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

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A role for proteinase-activated receptor-1 in inflammatory bowel diseases.

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type

label

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

@en

A role for proteinase-activated receptor-1 in inflammatory bowel diseases.

@nl

prefLabel

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

@en

A role for proteinase-activated receptor-1 in inflammatory bowel diseases.

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Journal of Clinical Investigation

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A role for proteinase-activated receptor-1 in inflammatory bowel diseases

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P2093

Andrea Mencarelli

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Giovanni Rizzo

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Giuseppe Cirino

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John L Wallace

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Laurie Cellars

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Martin Steinhoff

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Morley D Hollenberg

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Nathalie Vergnolle

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Nigel W Bunnett

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Patricia Andrade-Gordon

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P2860

Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells

Arginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretion

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

PARticipation in inflammation

Signalling pathways induced by protease-activated receptors and integrins in T cells

Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2

Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells

Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism

Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis

A protective role of protease-activated receptor 1 in rat gastric mucosa

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1444-1456

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10.1172/JCI21689

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15545995

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inflammatory bowel diseases

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526028

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