Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

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Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

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bilimsel makale

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scientific article published on 09 January 2017

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vedecký článok

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Chronic innate immune activati ...... regulates cellular metabolism.

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Chronic innate immune activati ...... regulates cellular metabolism.

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Chronic innate immune activati ...... regulates cellular metabolism.

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Chronic innate immune activati ...... regulates cellular metabolism.

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Chronic innate immune activati ...... regulates cellular metabolism.

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Chronic innate immune activati ...... regulates cellular metabolism.

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PNAS.1611113114

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Chronic innate immune activati ...... regulates cellular metabolism.

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P2093

Aktar Ali

http://www.w3.org/2001/XMLSchema#string

Maria A Calvaruso

http://www.w3.org/2001/XMLSchema#string

Maroof Hasan

http://www.w3.org/2001/XMLSchema#string

Nicole Dobbs

http://www.w3.org/2001/XMLSchema#string

Ralph J DeBerardinis

http://www.w3.org/2001/XMLSchema#string

Vijay K Gonugunta

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of STAT6 by STING is critical for antiviral innate immunity

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Trex1 prevents cell-intrinsic initiation of autoimmunity

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling.

Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation

P304

746-751

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scholarly article

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10.1073/PNAS.1611113114

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P407

English

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http://www.w3.org/2001/XMLSchema#string

P478

114

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P50

Guillermo Palchik

Nan Yan

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2017-01-09T00:00:00Z

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28069950

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P921

Interferon regulatory factor 3

Transmembrane protein 173

Three prime repair exonuclease 1

TANK-binding kinase 1

Leptin

P932

5278463

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