Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. - Wikidata - wikimedia - TriplyDB

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

http://www.wikidata.org/entity/Q37614860

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Under Pressure: Mechanical Stress Management in the Nucleus The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue Intermediate filament mechanics in vitro and in the cell: from coiled coils to filaments, fibers and networks Efficient extravasation of tumor-repopulating cells depends on cell deformability.Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion.Clusters of circulating tumor cells traverse capillary-sized vessels.Nuclear deformability and telomere dynamics are regulated by cell geometric constraints.Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments.Roles of endothelial A-type lamins in migration of T cells on and under endothelial layers.Cytoskeletal tension induces the polarized architecture of the nucleus.On-Chip Quantitative Measurement of Mechanical Stresses During Cell Migration with Emulsion Droplets.Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments.Extracellular Forces Cause the Nucleus to Deform in a Highly Controlled Anisotropic Manner.Nuclear migration events throughout development Stem cell mechanobiology: diverse lessons from bone marrow Regulation of lamin properties and functions: does phosphorylation do it all?Differential Predictive Roles of A- and B-Type Nuclear Lamins in Prostate Cancer Progression Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation Impact of the physical microenvironment on tumor progression and metastasis A high throughput approach for analysis of cell nuclear deformability at single cell level An open access microfluidic device for the study of the physical limits of cancer cell deformation during migration in confined environments.The tethering of chromatin to the nuclear envelope supports nuclear mechanics.Nuclear lamins and neurobiology.Whole genome expression profiling shows that BRG1 transcriptionally regulates UV inducible genes and other novel targets in human cells Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments Cellular mechanosensing: getting to the nucleus of it all.Repair of dense connective tissues via biomaterial-mediated matrix reprogramming of the wound interface Bioengineering paradigms for cell migration in confined microenvironments.From repair to regeneration: biomaterials to reprogram the meniscus wound microenvironment.Nanotopographical Surfaces for Stem Cell Fate Control: Engineering Mechanobiology from the Bottom Nuclear membrane diversity: underlying tissue-specific pathologies in disease?Fibroblasts Lead the Way: A Unified View of 3D Cell Motility Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion Screening cell mechanotype by parallel microfiltration Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells.Increased nuclear stiffness via FAK-ERK1/2 signaling is necessary for synthetic mechano-growth factor E peptide-induced tenocyte migration.Forces, fluctuations, and self-organization in the nucleus Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stress Nuclear envelope rupture and repair during cancer cell migration.Nuclear envelope proteins modulate proliferation of vascular smooth muscle cells during cyclic stretch application.

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P2860

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

http://www.wikidata.org/entity/Q37614860

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 February 2014

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

@en

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

@nl

type

label

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

@en

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

@nl

prefLabel

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

@en

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival.

@nl

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Journal of Cell Biology

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Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

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P2093

Avathamsa Athirasala

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Irena L Ivanovska

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Jae-Won Shin

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Kyle R Spinler

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Rocky Diegmiller

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Takamasa Harada

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

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669-682

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scholarly article

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10.1083/JCB.201308029

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5

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204

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P. C. Dave P. Dingal

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2014-02-24T00:00:00Z

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260379402

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24567359

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3941057

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