Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.
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Central Mechanisms Mediating Thrombospondin-4-induced Pain States.Emerging evidence for specific neuronal functions of auxiliary calcium channel α₂δ subunits.Thrombospondin-4 and excitatory synaptogenesis promote spinal sensitization after painful mechanical joint injury.Synaptic ultrastructure changes in trigeminocervical complex posttrigeminal nerve injury.Neuronal calcium signaling in chronic pain.Opioid-induced hyperalgesia in chronic pain patients and the mitigating effects of gabapentin.Injury-induced maladaptation and dysregulation of calcium channel α2 δ subunit proteins and its contribution to neuropathic pain development.The Anti-Allodynic Gabapentinoids: Myths, Paradoxes, and Acute Effects.Dynamic association of calcium channel subunits at the cellular membrane.Gabapentinoid Insensitivity after Repeated Administration is Associated with Down-Regulation of the α(2)δ-1 Subunit in Rats with Central Post-Stroke Pain HypersensitivityPainful Cervical Facet Joint Injury Is Accompanied by Changes in the Number of Excitatory and Inhibitory Synapses in the Superficial Dorsal Horn That Differentially Relate to Local Tissue Injury Severity.α2δ-1 Signaling Drives Cell Death, Synaptogenesis, Circuit Reorganization, and Gabapentin-Mediated Neuroprotection in a Model of Insult-Induced Cortical Malformation.Thrombospondin-4 acts on pre-synaptic calcium channel alpha-2-delta-1 subunit to induce synaptogenesis between sensory and spinal cord neurons through a T-type calcium channel dependent pathway that is blocked by early, low-dose gabapentin treatmentUpregulation of α₂δ-1 Calcium Channel Subunit in the Spinal Cord Contributes to Pelvic Organ Cross-Sensitization in a Rat Model of Experimentally-Induced Endometriosis.Neuropathic pain-induced enhancement of spontaneous and pain-evoked neuronal activity in the periaqueductal gray that is attenuated by gabapentin.
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P2860
Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Calcium channel α2δ1 proteins ...... ant excitatory synaptogenesis.
@en
Calcium channel α2δ1 proteins ...... ant excitatory synaptogenesis.
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type
label
Calcium channel α2δ1 proteins ...... ant excitatory synaptogenesis.
@en
Calcium channel α2δ1 proteins ...... ant excitatory synaptogenesis.
@nl
prefLabel
Calcium channel α2δ1 proteins ...... ant excitatory synaptogenesis.
@en
Calcium channel α2δ1 proteins ...... ant excitatory synaptogenesis.
@nl
P2093
P2860
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P1476
Calcium channel α2δ1 proteins ...... rant excitatory synaptogenesis
@en
P2093
Chunyi Zhou
Doo-Sik Kim
Kang-Wu Li
Kelli Sharp
Yanhui Peter Yu
Z David Luo
P2860
P304
P356
10.1074/JBC.M114.548990
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P577
2014-01-23T00:00:00Z