Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly
about
Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activityBiophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currentsStructural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels.Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channelsAntisense oligonucleotides against rat brain alpha1E DNA and its atrial homologue decrease T-type calcium current in atrial myocytesMolecular and functional diversity of voltage-gated calcium channels.Ca2+ current activation rate correlates with alpha 1 subunit density.T-type and N-type calcium channels of Xenopus oocytes: evidence for specific interactions with beta subunitsStructure and functional characterization of a novel human low-voltage activated calcium channel.Expression and pharmacology of endogenous Cav channels in SH-SY5Y human neuroblastoma cellsExpression of Calcium Channel Subunit Variants in Small Mesenteric Arteries of WKY and SHRFunctional properties of cardiac L-type calcium channels transiently expressed in HEK293 cells. Roles of alpha 1 and beta subunits.Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivationTissue-specific expression of splice variants of the mouse voltage-gated calcium channel alpha2/delta subunit.Expression of voltage-gated calcium channel α(2)δ(4) subunits in the mouse and rat retina.Variants in Ion Channel Genes Link Phenotypic Features of Bipolar Illness to Specific Neurobiological Process DomainsTargeting voltage-gated calcium channels for neuropathic pain management.Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.Complexes of the alpha1C and beta subunits generate the necessary signal for membrane targeting of class C L-type calcium channels.Spinal dorsal horn calcium channel alpha2delta-1 subunit upregulation contributes to peripheral nerve injury-induced tactile allodynia.Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells.Differential expression and association of calcium channel alpha1B and beta subunits during rat brain ontogeny.Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells.Beta1B subunit of voltage-dependent Ca2+ channels is predominant isoform expressed in human neuroblastoma cell line IMR32.Transmembrane auxiliary subunits of voltage-dependent ion channels.The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel.Differential effects of voltage-gated calcium channel blockers on calcium channel alpha-2-delta-1 subunit protein-mediated nociceptionCloning and deletion mutagenesis of the alpha2 delta calcium channel subunit from porcine cerebral cortex. Expression of a soluble form of the protein that retains [3H]gabapentin binding activity.Auxiliary subunits operate as a molecular switch in determining gating behaviour of the unitary N-type Ca2+ channel current in Xenopus oocytes.Identification of critical amino acids involved in alpha1-beta interaction in voltage-dependent Ca2+ channels.The alpha 2/delta subunit of voltage sensitive Ca2+ channels is a single transmembrane extracellular protein which is involved in regulated secretion.LTCC heteropentamer (open) transports Ca2+ from extracellular region to cytosol
P2860
Q21144219-A7422F46-1FF6-422B-ACEB-01C5D34BB66DQ24290750-3E170D4A-ECA3-44E8-BBCE-9AD66A6AF624Q24537292-4E7A9996-6E4D-4E31-9E8F-DDFE43977538Q24621422-00450D31-0AD5-408B-9927-E9218FD54CA0Q28263842-77CBA8A2-A9CA-452F-B883-89C8E937D5F9Q28571645-8CB4F75F-6505-4F30-9F0A-732DB6DDBA07Q33691491-8DE976C5-3702-48F4-BA72-9853E77ACE3EQ34040093-752DADEE-5E62-42F5-A4A2-9481EA3A1690Q34115407-B7FCD78C-252D-4287-9529-5F5145625156Q34490697-1E4AAEFC-C369-4A12-8C5A-98B07EFA9986Q34639654-C6AF8DF7-B068-4FB4-9DCE-8ECB60E9EE37Q36363454-76ED5BC9-E38B-44F8-8B06-86AE50A46358Q36411646-568F9569-FCCC-4870-ADC1-F80BF2A5726BQ36412553-4889B429-4774-40DE-8BAF-59C86262DDA2Q36836787-BCD34425-0E69-4AE7-99C2-683957E3C774Q37106997-F68478A3-A616-4118-9816-700955312569Q37200175-CEBFB52C-5370-4533-BB6C-F00C9569C705Q37605352-4162A9EF-8703-4EDB-8F48-51FCB6460241Q37622644-CBAA68CC-DC72-41D6-BD78-0BE24824ED4BQ37706465-657EECB7-5BB6-44F8-AFB9-A934AF655B15Q38321387-2FCDD111-2DA3-4BE5-928D-93DEF9D6B68CQ38329386-0BCF4D4C-B8AF-45B8-AE1D-D76B6311E62CQ39096400-4D4C743C-3112-4C6F-826B-02C6EA0F669FQ40537582-DA14AA8D-812E-461D-9E78-21AFAA8098C8Q41035583-90E24870-279C-40DD-8F38-8244D6C392E8Q41064407-B5138622-A775-401F-9BBC-2303A8E4C5BEQ41068271-4B5B8BCA-F6CE-4D28-BE1E-B9446E6C214EQ41204227-8DAB5960-A155-4789-8E2E-A56048738435Q41217429-E9364252-E49B-4DFD-89F5-9927D2B4563DQ41902234-E3C11F4F-6DA6-4DE0-8FDD-99FAF53AA09BQ48022953-3CC8FCAA-CB64-4232-9FDF-2A4F8CD4F912Q48916330-428C0F85-F1AF-4CC1-90FD-1F838E2CE22EQ49019394-EB0BD54D-D83F-4E49-80E5-2553DA5E2FB0Q49021762-D0D074FE-8CC2-4505-9B2B-D4B27F320AA2Q50296981-C386AB1A-F8C8-45D6-A3BB-88393C60DC8B
P2860
Human neuronal voltage-dependent calcium channels: studies on subunit structure and role in channel assembly
description
1993 nî lūn-bûn
@nan
1993 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Human neuronal voltage-depende ...... e and role in channel assembly
@ast
Human neuronal voltage-depende ...... e and role in channel assembly
@en
Human neuronal voltage-depende ...... e and role in channel assembly
@nl
type
label
Human neuronal voltage-depende ...... e and role in channel assembly
@ast
Human neuronal voltage-depende ...... e and role in channel assembly
@en
Human neuronal voltage-depende ...... e and role in channel assembly
@nl
prefLabel
Human neuronal voltage-depende ...... e and role in channel assembly
@ast
Human neuronal voltage-depende ...... e and role in channel assembly
@en
Human neuronal voltage-depende ...... e and role in channel assembly
@nl
P2093
P1433
P1476
Human neuronal voltage-depende ...... e and role in channel assembly
@en
P2093
E C Johnson
G Veliçelebi
M E Williams
M M Harpold
S Schoonmaker
S Simerson
P304
P356
10.1016/0028-3908(93)90004-M
P407
P577
1993-11-01T00:00:00Z