Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice
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Non-alcoholic fatty liver disease and type 2 diabetes mellitus: the liver disease of our age?Immune Imbalances in Non-Alcoholic Fatty Liver Disease: From General Biomarkers and Neutrophils to Interleukin-17 Axis Activation and New Therapeutic TargetsCrosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsmiR-217 regulates ethanol-induced hepatic inflammation by disrupting sirtuin 1-lipin-1 signaling.Microarray analysis of differentially expressed genes and their functions in omental visceral adipose tissues of pregnant women with vs. without gestational diabetes mellitus.TGF-β-induced hepatocyte lincRNA-p21 contributes to liver fibrosis in miceConophylline inhibits non-alcoholic steatohepatitis in miceEmerging role of adipokine apelin in hepatic remodelling and initiation of carcinogensis in chronic hepatitis C patientsProgression of diet induced nonalcoholic steatohepatitis is accompanied by increased expression of Kruppel-like-factor 10 in mice.A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitisMicro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitisHCC development is associated to peripheral insulin resistance in a mouse model of NASH.Potent natural products and herbal medicines for treating liver fibrosisSerum Fetuin-A Associated With Fatty Liver Index, Early Indicator of Nonalcoholic Fatty Liver Disease: A Strobe-Compliant Article.Myeloperoxidase-Hepatocyte-Stellate Cell Cross Talk Promotes Hepatocyte Injury and Fibrosis in Experimental Nonalcoholic SteatohepatitisNAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.A Cell-type-resolved Liver Proteome.The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer's Disease.TAK1 regulates hepatic cell survival and carcinogenesis.Advanced oxidation protein products induce hepatocyte epithelial-mesenchymal transition via a ROS-dependent, TGF-β/Smad signaling pathway.Protective effect of human serum amyloid P on CCl4-induced acute liver injury in miceIL6-mediated inflammatory loop reprograms normal to epithelial-mesenchymal transition+ metastatic cancer stem cells in preneoplastic liver of transforming growth factor beta-deficient β2-spectrin+/- mice.Ethanol Enhances TGF-β Activity by Recruiting TGF-β Receptors From Intracellular Vesicles/Lipid Rafts/Caveolae to Non-Lipid Raft Microdomains.miRNAs in non-alcoholic fatty liver disease.The kielin/chordin-like protein KCP attenuates nonalcoholic fatty liver disease in mice.Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β.Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways.Reply: To PMID 23996730.Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish.MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway.Protective effect of rimonabant, a canabinoid receptor 1 antagonist, on nonalcoholic fatty liver disease in a rat model through modulation of the hepatic expression of activin A and follistatin.Attenuating the rate of total body fat accumulation and alleviating liver damage by oral administration of vitamin D-enriched edible mushrooms in a diet-induced obesity murine model is mediated by an anti-inflammatory paradigm shift.Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression.High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine.Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis.Fatty acid synthase is required for profibrotic TGF-β signaling.To die or not to die: death signaling in nonalcoholic fatty liver disease.Apoptosis and non-alcoholic fatty liver diseases.Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis
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Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transforming growth factor bet ...... h and lipid metabolism in mice
@en
Transforming growth factor bet ...... and lipid metabolism in mice.
@nl
type
label
Transforming growth factor bet ...... h and lipid metabolism in mice
@en
Transforming growth factor bet ...... and lipid metabolism in mice.
@nl
prefLabel
Transforming growth factor bet ...... h and lipid metabolism in mice
@en
Transforming growth factor bet ...... and lipid metabolism in mice.
@nl
P2093
P2860
P356
P1433
P1476
Transforming growth factor bet ...... h and lipid metabolism in mice
@en
P2093
Ekihiro Seki
Jingyi Song
Rohit Loomba
Yoon Seok Roh
P2860
P304
P356
10.1002/HEP.26698
P407
P577
2013-12-18T00:00:00Z