Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
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Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP betaA high-affinity fully human anti-IL-6 mAb, 1339, for the treatment of multiple myelomaOsteoimmunology: interactions of the bone and immune systemArthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone lossAn Increased Risk of Osteoporosis during Acquired Immunodeficiency SyndromeImmune regulation of osteoclast function in postmenopausal osteoporosis: a critical interdisciplinary perspectiveThe role of estrogen and androgen receptors in bone health and diseaseIL-6 and IGF-1 Signaling Within and Between Muscle and Bone: How Important is the mTOR Pathway for Bone Metabolism?The Bone Marrow-Derived Stromal Cells: Commitment and Regulation of AdipogenesisAttenuation of the self-renewal of transit-amplifying osteoblast progenitors in the murine bone marrow by 17 beta-estradiolParathyroid hormone mediates hematopoietic cell expansion through interleukin-6Transgenic over-expression of plasminogen activator inhibitor-1 results in age-dependent and gender-specific increases in bone strength and mineralization.A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss.Acute inflammation induced by the biopsy of mouse mammary tumors promotes the development of metastasis.Follicle-stimulating hormone, interleukin-1, and bone density in adult women.Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment.Receptor recognition by gp130 cytokines.Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expressionReduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiationCD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in miceThe expression of osteoclastogenesis-associated factors and osteoblast response to osteolytic prostate cancer cells.IL-6 is required for airway mucus production induced by inhaled fungal allergensPasteurella multocida toxin induces IL-6, but not IL-1 alpha or TNF alpha in fibroblasts.Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. The role of the androgen receptorTGF-beta regulates the mechanical properties and composition of bone matrix.IL-6 in inflammation, immunity, and diseaseCytokine-mediated bone destruction in rheumatoid arthritis.IL6-174G/C polymorphism and fracture riskEstrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB siteSTAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity.Monitoring hormone replacement therapy by biochemical markers of bone metabolism in menopausal womenRegulation and function of trefoil factor family 3 expression in the biliary tree.M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.Lipopolysaccharide-inducible and salicylate-sensitive nuclear factor(s) on human tumor necrosis factor alpha promoterInterleukin-6 is required for a protective immune response to systemic Escherichia coli infectionAging and the musculoskeletal system.Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritisGlycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways.
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P2860
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1994
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@en
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@nl
type
label
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@en
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@nl
prefLabel
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@en
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@nl
P2093
P2860
P1433
P1476
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion.
@en
P2093
A Markatos
F Costantini
G Ciliberto
P2860
P304
P407
P577
1994-03-01T00:00:00Z