Mutations in p53 as potential molecular markers for human breast cancer.
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Compromised HOXA5 function can limit p53 expression in human breast tumoursHuman C6orf211 encodes Armt1, a protein carboxyl methyltransferase that targets PCNA and is linked to the DNA damage responseThe elimination of primer-dimer accumulation in PCRIncreased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancerChallenges to the development of antigen-specific breast cancer vaccines.Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cellsEnhancement of p53-dependent gene activation by the transcriptional coactivator Zac1p53 induces distinct epigenetic states at its direct target promoters.hMAGEA2 promotes progression of breast cancer by regulating Akt and Erk1/2 pathways.Antagonists of anaphase-promoting complex (APC)-2-cell cycle and apoptosis regulatory protein (CARP)-1 interaction are novel regulators of cell growth and apoptosis.Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells.BRCA1 and prostate cancer.Molecular mechanisms in cancer induction and prevention.Variable levels of chromosomal instability and mitotic spindle checkpoint defects in breast cancerMutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells.Prognostic significance of TP53 alterations in breast carcinoma.p53 mutation is associated with high S-phase fraction in primary fallopian tube adenocarcinoma.Allelic imbalance at chromosome 17p13.3 (YNZ22) in breast cancer is independent of p53 mutation or p53 overexpression and is associated with poor prognosis at medium-term follow-upDendritic cell immunotherapy for breast cancer.Triple negative breast cancer cell lines: one tool in the search for better treatment of triple negative breast cancer.Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patientEffect of Berry Extracts and Bioactive Compounds on Fulvestrant (ICI 182,780) Sensitive and Resistant Cell LinesWild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.Serum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breastPotential role of p53 on metallothionein induction in human epithelial breast cancer cellsDifferent mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cellsLoss of p53 protein during radiation transformation of primary human mammary epithelial cells.A gene signature-based approach identifies mTOR as a regulator of p73.Management of breast cancer by vaccine: fact or fiction.Cyclin E, a redundant cyclin in breast cancer.DNA damage triggers p21WAF1-dependent Emi1 down-regulation that maintains G2 arrest.Mitochondrial dysfunction in human breast cancer cells and their transmitochondrial cybrids.Ziyuglycoside I Inhibits the Proliferation of MDA-MB-231 Breast Carcinoma Cells through Inducing p53-Mediated G2/M Cell Cycle Arrest and Intrinsic/Extrinsic Apoptosis.Breast cancer vaccines: ongoing National Cancer Institute-registered clinical trials.The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.3,3'-Diindolylmethane (DIM) induces a G(1) cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21(WAF1/CIP1) expression.Nuclear accumulation of p53 protein correlates with mutations in the p53 gene on archival paraffin-embedded tissues of human breast cancer.Biological determinants of radioresistance and their remediation in pancreatic cancer.Disruption of the interaction between PMCA2 and calcineurin triggers apoptosis and enhances paclitaxel-induced cytotoxicity in breast cancer cells.Identification of microprocessor-dependent cancer cells allows screening for growth-sustaining micro-RNAs.
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Mutations in p53 as potential molecular markers for human breast cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Mutations in p53 as potential molecular markers for human breast cancer.
@en
Mutations in p53 as potential molecular markers for human breast cancer.
@nl
type
label
Mutations in p53 as potential molecular markers for human breast cancer.
@en
Mutations in p53 as potential molecular markers for human breast cancer.
@nl
prefLabel
Mutations in p53 as potential molecular markers for human breast cancer.
@en
Mutations in p53 as potential molecular markers for human breast cancer.
@nl
P2093
P2860
P356
P1476
Mutations in p53 as potential molecular markers for human breast cancer.
@en
P2093
P2860
P304
10657-10661
P356
10.1073/PNAS.88.23.10657
P407
P577
1991-12-01T00:00:00Z