Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells.
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Inhibition of p53 DNA binding by human papillomavirus E6 proteinsGps2, a protein partner for human papillomavirus E6 proteinsHuman papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityPresence of papillomavirus sequences in condylomatous lesions of the mamillae and in invasive carcinoma of the breast.Papillomavirus E6 oncoproteins.Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoterMultiple functions of human papillomavirus type 16 E6 contribute to the immortalization of mammary epithelial cellsHuman papillomavirus type 16 E6-induced degradation of E6TP1 correlates with its ability to immortalize human mammary epithelial cells.Signals that dictate nuclear localization of human papillomavirus type 16 oncoprotein E6 in living cellsThe Epstein-Barr virus immediate-early protein BZLF1 regulates p53 function through multiple mechanismsImmortalization of distinct human mammary epithelial cell types by human papilloma virus 16 E6 or E7.Viral oncogenes, noncoding RNAs, and RNA splicing in human tumor virusesHPV16 early gene E5 specifically reduces miRNA-196a in cervical cancer cells.Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53.Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein.Mutational analysis of human papillomavirus type 16 E6 demonstrates that p53 degradation is necessary for immortalization of mammary epithelial cells.Serum- and calcium-induced differentiation of human keratinocytes is inhibited by the E6 oncoprotein of human papillomavirus type 16.Transcriptomic analyses of genes differentially expressed by high-risk and low-risk human papilloma virus E6 oncoproteinsComparative analysis of p73 and p53 regulation and effector functions.Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndromeComparison of the properties of the E6 and E7 genes of low- and high-risk cutaneous papillomaviruses reveals strongly transforming and high Rb-binding activity for the E7 protein of the low-risk human papillomavirus type 1.Loss of p53 protein during radiation transformation of primary human mammary epithelial cells.Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells.Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion by targeting focal adhesion pathways in cervical squamous cell carcinoma.Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesViral oncoproteins discriminate between p53 and the p53 homolog p73.Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arresthAda3 degradation by papillomavirus type 16 E6 correlates with abrogation of the p14ARF-p53 pathway and efficient immortalization of human mammary epithelial cellsRegulation of DNA synthesis in division-arrested mouse C127 cells permissive for bovine papillomavirus DNA amplification.Myc and human papillomavirus type 16 E7 genes cooperate to immortalize human keratinocytes.Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner.Predicted alpha-helix/beta-sheet secondary structures for the zinc-binding motifs of human papillomavirus E7 and E6 proteins by consensus prediction averaging and spectroscopic studies of E7A mathematical model for the onset of avascular tumor growth in response to the loss of p53 function.HPV16 E6 Promotes Breast Cancer Proliferation via Upregulation of COX-2 Expression.
P2860
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P2860
Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells.
description
1993 nî lūn-bûn
@nan
1993 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@ast
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@en
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@nl
type
label
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@ast
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@en
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@nl
prefLabel
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@ast
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@en
Enhanced degradation of p53 pr ...... uman mammary epithelial cells.
@nl
P2093
P2860
P1433
P1476
Enhanced degradation of p53 pr ...... human mammary epithelial cells
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1993.TB05833.X
P407
P577
1993-05-01T00:00:00Z