FVIIa as used pharmacologically is not TF dependent in hemophilia B mice
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Pharmacological concentrations of recombinant factor VIIa restore hemostasis independent of tissue factor in antibody-induced hemophilia mice.Structure-Function Relationship of the Interaction between Tissue Factor and Factor VIIa.Gene Delivery of Activated Factor VII Using Alternative Adeno-Associated Virus Serotype Improves Hemostasis in Hemophiliac Mice with FVIII Inhibitors and Adeno-Associated Virus Neutralizing Antibodies.The endothelial protein C receptor enhances hemostasis of FVIIa administration in hemophilic mice in vivo.Kinetic analysis and binding studies of a new recombinant human factor VIIa for treatment of haemophilia.Predicting dosing advantages of factor VIIa variants with altered tissue factor-dependent and lipid-dependent activities.Recombinant factor VIIa addition to haemophilic blood perfused over collagen/tissue factor can sufficiently bypass the factor IXa/VIIIa defect to rescue fibrin generation.An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.Recombinant human factor VIIa (rFVIIa) in hemophilia: mode of action and evidence to date.
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FVIIa as used pharmacologically is not TF dependent in hemophilia B mice
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice
@en
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice.
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type
label
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice
@en
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice.
@nl
prefLabel
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice
@en
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice.
@nl
P2093
P2860
P921
P1433
P1476
FVIIa as used pharmacologically is not TF dependent in hemophilia B mice
@en
P2093
Darrel W Stafford
Dengmin Feng
Herbert Whinna
P2860
P304
P356
10.1182/BLOOD-2013-08-522987
P407
P577
2014-01-14T00:00:00Z