New cytochrome P450 mechanisms: implications for understanding molecular basis for drug toxicity at the level of the cytochrome.
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Alternative strategies for carcinogenicity assessment: an efficient and simplified approach based on in vitro mutagenicity and cell transformation assays.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Structure-activity relationship models for rat carcinogenesis and assessing the role mutagens play in model predictivityIncreased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease.Toxicology mechanism of the persistent organic pollutants (POPs) in fish through AhR pathway.The new ISSMIC database on in vivo micronucleus and its role in assessing genotoxicity testing strategies.The difficulties of polytherapy: examples from antimicrobial chemotherapy.Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications.Functioning of drug-metabolizing microsomal cytochrome P450s: In silico probing of proteins suggests that the distal heme 'active site' pocket plays a relatively 'passive role' in some enzyme-substrate interactionsExploring In Vitro/In Vivo Correlation: Lessons Learned from Analyzing Phase I Results of the US EPA's ToxCast Project
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New cytochrome P450 mechanisms: implications for understanding molecular basis for drug toxicity at the level of the cytochrome.
description
article científic
@ca
article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on January 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@en
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@nl
type
label
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@en
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@nl
prefLabel
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@en
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@nl
P2860
P1476
New cytochrome P450 mechanisms ...... t the level of the cytochrome.
@en
P2093
Narasimhulu Shakunthala
P2860
P356
10.1517/17425250903329095
P407
P577
2010-01-01T00:00:00Z