Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase.
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Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent mannersExpression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.Glycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascadesTargeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancerNovel drugs and therapeutic targets for severe mood disorders.Functional consequence of the MET-T1010I polymorphism in breast cancerGSK3beta is a negative regulator of platelet function and thrombosis.Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblastsMetabolic reprogramming in dietary restriction.Tissue-specific role of glycogen synthase kinase 3beta in glucose homeostasis and insulin action.Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiationGlycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.Coordinating Gene Expression and Axon Assembly to Control Axon Growth: Potential Role of GSK3 SignalingConjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner.Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription.Dendritic cell maturation occurs through the inhibition of GSK-3β.β-arrestin 2 regulates Toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3β.A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.
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Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@en
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@nl
type
label
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@en
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@nl
prefLabel
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@en
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@nl
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P356
P1476
Glycogen synthase kinase 3beta ...... f the c-Jun N-terminal kinase.
@en
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Gordon B Mills
Hong-Ji Xu
Ruth Lapushin
Shuangxing Yu
Shuying Liu
Xianjun Fang
Yutaka Hasegawa
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P304
51075-51081
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10.1074/JBC.M408607200
P407
P577
2004-10-01T00:00:00Z