Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression.
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Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cellsA mouse model for Costello syndrome reveals an Ang II-mediated hypertensive conditionUVB-induced apoptosis drives clonal expansion during skin tumor developmentThe molecular etiology and prevention of estrogen-initiated cancers: Ockham's Razor: Pluralitas non est ponenda sine necessitate. Plurality should not be posited without necessityAntagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesisA review of the molecular mechanisms of chemically induced neoplasia in rat and mouse models in National Toxicology Program bioassays and their relevance to human cancerAnimal Models of Chemical Carcinogenesis: Driving Breakthroughs in Cancer Research for 100 YearsCarcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.Analysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone.PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signalingGenetic events and the role of TGF beta in epithelial tumour progression.The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals.Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sitesCarcinogenesis in mouse and human cells: parallels and paradoxes.Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis modelTumor formation initiated by nondividing epidermal cells via an inflammatory infiltrateIntratumor heterogeneity of K-ras2 mutations in colorectal adenocarcinomas: association with degree of DNA aneuploidyRole of proto-oncogene activation in carcinogenesis.Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.Alterations in signal transduction pathways implicated in tumour progression during multistage mouse skin carcinogenesis.Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications.Mutations in ras genes in cells cultured from mouse skin tumors induced by ultraviolet irradiation.Specific K-ras2 mutations in human sporadic colorectal adenomas are associated with DNA near-diploid aneuploidy and inhibition of proliferation.Development of keratoacanthomas and squamous cell carcinomas in transgenic rabbits with targeted expression of EJras oncogene in epidermis.Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis.The role of polycyclic aromatic hydrocarbon-DNA adducts in inducing mutations in mouse skinLoss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cellsA role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis.Genetic changes during mouse skin tumorigenesis.Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer.Lack of ecotropic virus involvement in induction of lymphomas in DBA/2J mice by 7,12-dimethylbenz(a)anthracene.Rat p53 gene mutations in primary Zymbal gland tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline, a food mutagen.Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf).BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling.A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesisEarly mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage.Molecular mechanisms of ultraviolet radiation carcinogenesis.
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Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Carcinogen-induced mutations i ...... athways for tumor progression.
@en
Carcinogen-induced mutations i ...... athways for tumor progression.
@nl
type
label
Carcinogen-induced mutations i ...... athways for tumor progression.
@en
Carcinogen-induced mutations i ...... athways for tumor progression.
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prefLabel
Carcinogen-induced mutations i ...... athways for tumor progression.
@en
Carcinogen-induced mutations i ...... athways for tumor progression.
@nl
P2093
P2860
P356
P1476
Carcinogen-induced mutations i ...... athways for tumor progression.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.2.538
P407
P577
1990-01-01T00:00:00Z